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GRF4 growth-regulating factor 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824457, updated on 18-Sep-2024

Summary

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Official Symbol
GRF4
Official Full Name
growth-regulating factor 4
Primary source
TAIR:AT3G52910
Locus tag
AT3G52910
See related
Araport:AT3G52910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtGRF4; growth-regulating factor 4
Summary
Growth regulating factor encoding transcription activator. One of the nine members of a GRF gene family, containing nuclear targeting domain. Involved in leaf development and expressed in root, shoot and flower.
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Genomic context

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See GRF4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (19615977..19618507, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene KCBP-interacting protein kinase Neighboring gene RAB6-interacting golgin (DUF662) Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene transcriptional activator (DUF662) Neighboring gene Aldolase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The transcription factor AtGRF5 and the transcription coactivator AN3 regulate cell proliferation in leaf primordia of Arabidopsis thaliana. Horiguchi G, et al. Plant J, 2005 Jul. PMID 15960617
  2. The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis. Kim JH, et al. Plant J, 2003 Oct. PMID 12974814
  3. Molecular mechanism of microRNA396 mediating pistil development in Arabidopsis. Liang G, et al. Plant Physiol, 2014 Jan. PMID 24285851, Free PMC Article
  4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115151.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within leaf development TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
growth-regulating factor 4
NP_190859.2
  • growth-regulating factor 4 (GRF4); CONTAINS InterPro DOMAIN/s: Glutamine-Leucine-Glutamine, QLQ (InterPro:IPR014978), WRC (InterPro:IPR014977); BEST Arabidopsis thaliana protein match is: growth-regulating factor 3 (TAIR:AT2G36400.1); Has 959 Blast hits to 852 proteins in 46 species: Archae - 0; Bacteria - 4; Metazoa - 66; Fungi - 4; Plants - 523; Viruses - 0; Other Eukaryotes - 362 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19615977..19618507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115151.3 → NP_190859.2  growth-regulating factor 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190859.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L8A7, Q9LFA0
    UniProtKB/TrEMBL
    A0A5S9XKD9, A0A654FHT9
    Conserved Domains (2) summary
    pfam08879
    Location:152 → 193
    WRC
    pfam08880
    Location:83 → 116
    QLQ
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8L8A7.1

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