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VPS35C VPS35 homolog C [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824294, updated on 18-Sep-2024

Summary

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Official Symbol
VPS35C
Official Full Name
VPS35 homolog C
Primary source
TAIR:AT3G51310
Locus tag
AT3G51310
See related
Araport:AT3G51310
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
VPS35 homolog C
Summary
Homolog of yeast retromer subunit VPS35. Part of a retromer-like protein complex involved in endosome to lysosome protein transport.
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Genomic context

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See VPS35C in Genome Data Viewer
Location:
chromosome: 3
Exon count:
21
Sequence:
Chromosome: 3; NC_003074.8 (19044331..19049454, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene protein serine/threonine kinase Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene pyridoxal-phosphate-dependent serine hydroxymethyltransferase, putative (DUF632) Neighboring gene RHO-related protein from plants 1 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene RING/U-box superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis VPS35, a retromer component, is required for vacuolar protein sorting and involved in plant growth and leaf senescence. Yamazaki M, et al. Plant Cell Physiol, 2008 Feb. PMID 18222962
  2. Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. Oliviusson P, et al. Plant Cell, 2006 May. PMID 16582012, Free PMC Article
  3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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NM_114990.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endosome to lysosome transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in retrograde transport, endosome to Golgi IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in multivesicular body IDA
Inferred from Direct Assay
more info
 PubMed 
part_of retromer complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of retromer complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of retromer, cargo-selective complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
VPS35 homolog C
NP_190699.3
  • VPS35 homolog C (VPS35C); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: intracellular protein transport, endosome to lysosome transport, retrograde transport, endosome to Golgi; LOCATED IN: microsome, retromer complex, membrane, multivesicular body; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Vacuolar protein sorting-associated protein 35 (InterPro:IPR005378); BEST Arabidopsis thaliana protein match is: VPS35 homolog A (TAIR:AT2G17790.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19044331..19049454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114990.5 → NP_190699.3  VPS35 homolog C [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190699.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8R7K9, Q9SD18
    UniProtKB/TrEMBL
    A0A178VKA9
    Conserved Domains (1) summary
    pfam03635
    Location:9 → 747
    Vps35; Vacuolar protein sorting-associated protein 35
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8R7K9.1

Gene LinkOut

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