MUR1 NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: MUR1
Official Full Name: NAD(P)-binding Rossmann-fold superfamily protein
Primary source: TAIR:AT3G51160
Locus tag: AT3G51160
See related: Araport:AT3G51160
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 6-DEHYDRATASE; 6-DEHYDRATASE 2; GDP-D-MANNOSE-4; GMD2; MURUS 1; MUR_1
Summary: Catalyzes the first step in the de novo synthesis of GDP-L-fucose.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

MUR1 role in the freezing tolerance in Arabidopsis.
Title: MUR1-mediated cell-wall fucosylation is required for freezing tolerance in Arabidopsis thaliana.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_114976.4

Function	Evidence Code	Pubs
enables GDP-mannose 4,6-dehydratase activity	IDA Inferred from Direct Assay more info	PubMed
enables GDP-mannose 4,6-dehydratase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in 'de novo' GDP-L-fucose biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within 'de novo' GDP-L-fucose biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in GDP-mannose metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within unidimensional cell growth	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_190685.2

MURUS 1 (MUR1); FUNCTIONS IN: GDP-mannose 4,6-dehydratase activity; INVOLVED IN: 'de novo' GDP-L-fucose biosynthetic process, unidimensional cell growth; LOCATED IN: cytosol; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), GDP-mannose 4,6-dehydratase (InterPro:IPR006368); BEST Arabidopsis thaliana protein match is: GDP-D-mannose 4,6-dehydratase 1 (TAIR:AT5G66280.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).