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Cytidine/deoxycytidylate deaminase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824013, updated on 18-Sep-2024

Summary

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Official Full Name
Cytidine/deoxycytidylate deaminase family protein
Primary source
TAIR:AT3G48540
Locus tag
AT3G48540
See related
Araport:AT3G48540
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (17989798..17992039, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene SNF1-related protein kinase regulatory subunit gamma 1 Neighboring gene SHOOT GRAVITROPISM-like protein Neighboring gene chlorsulfuron/imidazolinone resistant 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development. Niehaus M, et al. Plant Cell, 2022 Sep 27. PMID 35861422, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_114712.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Cytidine/deoxycytidylate deaminase family protein
NP_190423.2
  • Cytidine/deoxycytidylate deaminase family protein; FUNCTIONS IN: hydrolase activity, zinc ion binding, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: APOBEC/CMP deaminase, zinc-binding (InterPro:IPR016192), CMP/dCMP deaminase, zinc-binding (InterPro:IPR002125), Cytidine deaminase-like (InterPro:IPR016193), Cytidine deaminase (InterPro:IPR015517); Has 3737 Blast hits to 3733 proteins in 1421 species: Archae - 65; Bacteria - 2323; Metazoa - 218; Fungi - 134; Plants - 52; Viruses - 89; Other Eukaryotes - 856 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    17989798..17992039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114712.3 → NP_190423.2  Cytidine/deoxycytidylate deaminase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190423.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VIX5, A0A384KB52, A0MF13, Q1PEH3
    Conserved Domains (1) summary
    cd01286
    Location:69 → 182
    deoxycytidylate_deaminase; Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the ...
Nucleotide Protein
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