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TOPP5 type one serine/threonine protein phosphatase 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823835, updated on 18-Sep-2024

Summary

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Official Symbol
TOPP5
Official Full Name
type one serine/threonine protein phosphatase 5
Primary source
TAIR:AT3G46820
Locus tag
AT3G46820
See related
Araport:AT3G46820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
type one serine/threonine protein phosphatase 5
Summary
Encodes the catalytic subunit of a Type 1 phosphoprotein Ser/Thr phosphatase, expressed in roots, shoots and flowers.
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Genomic context

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See TOPP5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (17241702..17244281, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene RAB GTPase homolog A2C Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of Protein Phosphatase1 Regulatory Subunit3 in Mediating the Abscisic Acid Response. Zhang J, et al. Plant Physiol, 2020 Nov. PMID 32948668, Free PMC Article
  2. Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana. Smith RD, et al. Plant Mol Biol, 1993 Jan. PMID 7678768
  3. Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit. Templeton GW, et al. Biochem J, 2011 Apr 1. PMID 21222654
  4. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
  5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_114549.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to abscisic acid stimulus IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
part_of protein phosphatase type 1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
type one serine/threonine protein phosphatase 5
NP_190266.1
  • type one serine/threonine protein phosphatase 5 (TOPP5); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 2 (TAIR:AT5G59160.3); Has 7127 Blast hits to 6926 proteins in 615 species: Archae - 78; Bacteria - 490; Metazoa - 2413; Fungi - 1415; Plants - 987; Viruses - 13; Other Eukaryotes - 1731 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    17241702..17244281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114549.4 → NP_190266.1  type one serine/threonine protein phosphatase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190266.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48485, Q29Q41, Q570F3
    UniProtKB/TrEMBL
    A0A178VFV2, A0A5S9XIK6, A0A7G2ET45
    Conserved Domains (1) summary
    cd07414
    Location:13 → 304
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48485.1

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