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RABE1c RAB GTPase homolog 8A [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823749, updated on 18-Sep-2024

Summary

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Official Symbol
RABE1c
Official Full Name
RAB GTPase homolog 8A
Primary source
TAIR:AT3G46060
Locus tag
AT3G46060
See related
Araport:AT3G46060
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARA-3; ARA3; ATRAB8A; ATRABE1C; RAB GTPase homolog 8A; RAB8A; SMALL GTP-BINDING PROTEIN
Summary
small GTP-binding protein (ara-3)
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Genomic context

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See RABE1c in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (16917527..16920018)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15A D Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene C2H2-type zinc finger family protein Neighboring gene C2H2-type zinc finger family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A ras-related small GTP-binding protein, RabE1c, regulates stomatal movements and drought stress responses by mediating the interaction with ABA receptors. Chen D, et al. Plant Sci, 2021 May. PMID 33775364
  2. Ethylene regulates monomeric GTP-binding protein gene expression and activity in Arabidopsis. Moshkov IE, et al. Plant Physiol, 2003 Apr. PMID 12692329, Free PMC Article
  3. Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process. Huang FC, et al. Plant Cell Physiol, 2021 Dec 3. PMID 34255832
  4. Isolation and analysis of cDNAs encoding small GTP-binding proteins of Arabidopsis thaliana. Anai T, et al. Gene, 1991 Dec 15. PMID 1748311
  5. Arabidopsis Rab-E GTPases exhibit a novel interaction with a plasma-membrane phosphatidylinositol-4-phosphate 5-kinase. Camacho L, et al. J Cell Sci, 2009 Dec 1. PMID 19903693

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process.
    Title: Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process.
  2. RabE1c binds PEX7 and facilitates PEX7 degradation in the presence of immobile GFP-PEX7 accumulated at the membrane [RabE1c]
    Title: Proteomic analysis reveals that the Rab GTPase RabE1c is involved in the degradation of the peroxisomal protein receptor PEX7 (peroxin 7).
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001084779.1
NM_001125308.1
NM_114475.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within ethylene-activated signaling pathway IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
RAB GTPase homolog 8A
NP_001078248.1
  • ARA3; FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29695 Blast hits to 29627 proteins in 805 species: Archae - 22; Bacteria - 171; Metazoa - 15449; Fungi - 4249; Plants - 3560; Viruses - 20; Other Eukaryotes - 6224 (source: NCBI BLink).
NP_001118780.1
  • ARA3; FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_190192.1
  • RAB GTPase homolog 8A (RAB8A); FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29695 Blast hits to 29627 proteins in 805 species: Archae - 22; Bacteria - 171; Metazoa - 15449; Fungi - 4249; Plants - 3560; Viruses - 20; Other Eukaryotes - 6224 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    16917527..16920018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114475.4 → NP_190192.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190192.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28186
    UniProtKB/TrEMBL
    A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
    Conserved Domains (1) summary
    cd01867
    Location:13 → 180
    Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

  2. NM_001125308.1 → NP_001118780.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001118780.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28186
    UniProtKB/TrEMBL
    A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
    Conserved Domains (1) summary
    cd01867
    Location:13 → 180
    Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

  3. NM_001084779.1 → NP_001078248.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078248.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28186
    UniProtKB/TrEMBL
    A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
    Conserved Domains (1) summary
    cd01867
    Location:13 → 180
    Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28186.1

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