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LAS1 lanosterol synthase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823649, updated on 18-Sep-2024

Summary

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Official Symbol
LAS1
Official Full Name
lanosterol synthase 1
Primary source
TAIR:AT3G45130
Locus tag
AT3G45130
See related
Araport:AT3G45130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
lanosterol synthase 1
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Genomic context

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See LAS1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
19
Sequence:
Chromosome: 3; NC_003074.8 (16512170..16517781, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lanosterol synthase in dicotyledonous plants. Suzuki M, et al. Plant Cell Physiol, 2006 May. PMID 16531458
  2. Lanosterol biosynthesis in plants. Kolesnikova MD, et al. Arch Biochem Biophys, 2006 Mar 1. PMID 16445886
  3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_001339196.1
NM_001339197.1
NM_114382.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lanosterol synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in triterpenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
lanosterol synthase 1
NP_190099.3
  • lanosterol synthase 1 (LAS1); CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: cycloartenol synthase 1 (TAIR:AT2G07050.1); Has 2160 Blast hits to 1916 proteins in 566 species: Archae - 4; Bacteria - 1015; Metazoa - 82; Fungi - 243; Plants - 610; Viruses - 0; Other Eukaryotes - 206 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    16512170..16517781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339194.1 → NP_001327790.1  lanosterol synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LTE4, A0A7G2EU13

  2. NM_001339195.1 → NP_001327789.1  lanosterol synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LTE4, A0A7G2EU13

  3. NM_114382.5 → NP_190099.3  lanosterol synthase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190099.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LTE2, Q1G1A4, Q9M1U6
    UniProtKB/TrEMBL
    A0A5S9XJK9, A0A654FE86, A0A7G2EU13
    Conserved Domains (1) summary
    PLN03012
    Location:1 → 751
    PLN03012; Camelliol C synthase

  4. NM_001339196.1 → NP_001327788.1  lanosterol synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LTE2, Q1G1A4, Q9M1U6
    UniProtKB/TrEMBL
    A0A5S9XJK9, A0A654FE86, A0A7G2EU13
    Conserved Domains (1) summary
    PLN03012
    Location:1 → 751
    PLN03012; Camelliol C synthase

  5. NM_001339197.1 → NP_001327787.1  lanosterol synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LTE2, Q1G1A4, Q9M1U6
    UniProtKB/TrEMBL
    A0A5S9XJK9, A0A654FE86, A0A7G2EU13
    Conserved Domains (1) summary
    PLN03012
    Location:1 → 751
    PLN03012; Camelliol C synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1G1A4.1

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