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UVH3 5'-3' exonuclease family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822427, updated on 18-Sep-2024

Summary

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Official Symbol
UVH3
Official Full Name
5'-3' exonuclease family protein
Primary source
TAIR:AT3G28030
Locus tag
AT3G28030
See related
Araport:AT3G28030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ULTRAVIOLET HYPERSENSITIVE 3; UV REPAIR DEFECTIVE 1; UVR1
Summary
Required for repair of pyrimidine-pyrimidinone (6-4) dimers.
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Genomic context

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See UVH3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
18
Sequence:
Chromosome: 3; NC_003074.8 (10424179..10431364)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DNA-binding protein Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene nodulin MtN21 /EamA-like transporter family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ultraviolet B radiation enhances a phytochrome-B-mediated photomorphogenic response in Arabidopsis. Boccalandro HE, et al. Plant Physiol, 2001 Jun. PMID 11402206, Free PMC Article
  2. UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. Jiang CZ, et al. Genetics, 1997 Nov. PMID 9383080, Free PMC Article
  3. Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance. Larkindale J, et al. Plant Physiol, 2005 Jun. PMID 15923322, Free PMC Article
  4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
  5. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001338928.1
NM_001338929.1
NM_001338930.1
NM_001338931.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within non-photoreactive DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to UV-B IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to heat IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
5'-3' exonuclease family protein
NP_001319661.1
  • ULTRAVIOLET HYPERSENSITIVE 3 (UVH3); FUNCTIONS IN: protein binding, nuclease activity; INVOLVED IN: DNA repair, response to UV-B, response to heat, non-photoreactive DNA repair; LOCATED IN: nucleus; EXPRESSED IN: stem, leaf whorl, seed; EXPRESSED DURING: E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), Xeroderma pigmentosum group G protein (InterPro:IPR001044), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G01880.1); Has 8115 Blast hits to 5779 proteins in 624 species: Archae - 528; Bacteria - 414; Metazoa - 2441; Fungi - 1496; Plants - 576; Viruses - 71; Other Eukaryotes - 2589 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    10424179..10431364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001338928.1 → NP_001319661.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ATY5, Q9LRT2
    UniProtKB/TrEMBL
    A0A2H1ZEJ7

  2. NM_001338929.1 → NP_001325749.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VB00, A0A1I9LM67

  3. NM_001338930.1 → NP_001325748.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ATY5, Q9LRT2
    UniProtKB/TrEMBL
    A0A1I9LM66

  4. NM_001338931.1 → NP_001325750.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LM68
Nucleotide Protein
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