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G6PD5 glucose-6-phosphate dehydrogenase 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822349, updated on 18-Sep-2024

Summary

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Official Symbol
G6PD5
Official Full Name
glucose-6-phosphate dehydrogenase 5
Primary source
TAIR:AT3G27300
Locus tag
AT3G27300
See related
Araport:AT3G27300
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
glucose-6-phosphate dehydrogenase 5
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Genomic context

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See G6PD5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Sequence:
Chromosome: 3; NC_003074.8 (10083009..10086798, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene prohibitin 4 Neighboring gene miscRNA Neighboring gene RNI-like superfamily protein Neighboring gene plant UBX domain-containing protein 1 Neighboring gene alpha/beta-Hydrolases superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternative splicing of Arabidopsis G6PD5 recruits NADPH-producing OPPP reactions to the endoplasmic reticulum. Linnenbrügger L, et al. Front Plant Sci, 2022. PMID 36119606, Free PMC Article
  2. Involvement of G6PD5 in ABA response during seed germination and root growth in Arabidopsis. Yang L, et al. BMC Plant Biol, 2019 Jan 30. PMID 30700259, Free PMC Article
  3. Functional analyses of cytosolic glucose-6-phosphate dehydrogenases and their contribution to seed oil accumulation in Arabidopsis. Wakao S, et al. Plant Physiol, 2008 Jan. PMID 17993547, Free PMC Article
  4. Genome-wide analysis of glucose-6-phosphate dehydrogenases in Arabidopsis. Wakao S, et al. Plant J, 2005 Jan. PMID 15634201
  5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. involvement in ABA response during seed germination and root growth
    Title: Involvement of G6PD5 in ABA response during seed germination and root growth in Arabidopsis.
  2. results suggest that loss of cytosolic G6PDH activity affects the metabolism of developing seeds by increasing carbon substrates for synthesis of storage compounds rather than by decreasing the NADPH supply specifically for fatty acid synthesis
    Title: Functional analyses of cytosolic glucose-6-phosphate dehydrogenases and their contribution to seed oil accumulation in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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NM_001035703.3
NM_001084745.1
NM_001338866.1
NM_001338867.1
NM_113644.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables glucose-6-phosphate dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-6-phosphate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glucose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within pentose-phosphate shunt, oxidative branch IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
is_active_in cytoplasmic side of endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
glucose-6-phosphate dehydrogenase 5
NP_001030780.1
  • glucose-6-phosphate dehydrogenase 5 (G6PD5); FUNCTIONS IN: glucose-6-phosphate dehydrogenase activity; INVOLVED IN: response to cadmium ion, pentose-phosphate shunt, oxidative branch, glucose metabolic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glucose-6-phosphate dehydrogenase, active site (InterPro:IPR019796), Glucose-6-phosphate dehydrogenase, C-terminal (InterPro:IPR022675), NAD(P)-binding domain (InterPro:IPR016040), Glucose-6-phosphate dehydrogenase (InterPro:IPR001282), Glucose-6-phosphate dehydrogenase, NAD-binding (InterPro:IPR022674); BEST Arabidopsis thaliana protein match is: glucose-6-phosphate dehydrogenase 6 (TAIR:AT5G40760.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001078214.1
  • glucose-6-phosphate dehydrogenase 5 (G6PD5); FUNCTIONS IN: glucose-6-phosphate dehydrogenase activity; INVOLVED IN: pentose-phosphate shunt, oxidative branch, glucose metabolic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glucose-6-phosphate dehydrogenase, active site (InterPro:IPR019796), Glucose-6-phosphate dehydrogenase, C-terminal (InterPro:IPR022675), NAD(P)-binding domain (InterPro:IPR016040), Glucose-6-phosphate dehydrogenase (InterPro:IPR001282), Glucose-6-phosphate dehydrogenase, NAD-binding (InterPro:IPR022674); BEST Arabidopsis thaliana protein match is: glucose-6-phosphate dehydrogenase 6 (TAIR:AT5G40760.1); Has 8384 Blast hits to 8367 proteins in 2341 species: Archae - 0; Bacteria - 5762; Metazoa - 904; Fungi - 180; Plants - 377; Viruses - 4; Other Eukaryotes - 1157 (source: NCBI BLink).
NP_189366.1
  • glucose-6-phosphate dehydrogenase 5 (G6PD5); FUNCTIONS IN: glucose-6-phosphate dehydrogenase activity; INVOLVED IN: response to cadmium ion, pentose-phosphate shunt, oxidative branch, glucose metabolic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glucose-6-phosphate dehydrogenase, active site (InterPro:IPR019796), Glucose-6-phosphate dehydrogenase, C-terminal (InterPro:IPR022675), NAD(P)-binding domain (InterPro:IPR016040), Glucose-6-phosphate dehydrogenase (InterPro:IPR001282), Glucose-6-phosphate dehydrogenase, NAD-binding (InterPro:IPR022674); BEST Arabidopsis thaliana protein match is: glucose-6-phosphate dehydrogenase 6 (TAIR:AT5G40760.1); Has 8384 Blast hits to 8367 proteins in 2341 species: Archae - 0; Bacteria - 5762; Metazoa - 904; Fungi - 180; Plants - 377; Viruses - 4; Other Eukaryotes - 1157 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    10083009..10086798 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113644.5 → NP_189366.1  glucose-6-phosphate dehydrogenase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189366.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZD0, Q9LK23, Q9SUK0
    UniProtKB/TrEMBL
    A0A178VBL3, A0A5S9XG42, Q5E919
    Conserved Domains (3) summary
    PLN02539
    Location:15 → 509
    PLN02539; glucose-6-phosphate 1-dehydrogenase
    pfam00479
    Location:35 → 221
    G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
    pfam02781
    Location:224 → 511
    G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain

  2. NM_001035703.3 → NP_001030780.1  glucose-6-phosphate dehydrogenase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030780.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZD0, Q9LK23, Q9SUK0
    UniProtKB/TrEMBL
    A0A178VBL3, A0A5S9XG42, Q5E919
    Conserved Domains (3) summary
    PLN02539
    Location:15 → 509
    PLN02539; glucose-6-phosphate 1-dehydrogenase
    pfam00479
    Location:35 → 221
    G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
    pfam02781
    Location:224 → 511
    G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain

  3. NM_001338866.1 → NP_001325679.1  glucose-6-phosphate dehydrogenase 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VBL3, A0A1I9LLZ6, A0A5S9XG42

  4. NM_001084745.1 → NP_001078214.1  glucose-6-phosphate dehydrogenase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078214.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZD0, Q9LK23, Q9SUK0
    UniProtKB/TrEMBL
    A0A178VBL3, A0A5S9XG42, Q5E919
    Conserved Domains (3) summary
    PLN02539
    Location:15 → 509
    PLN02539; glucose-6-phosphate 1-dehydrogenase
    pfam00479
    Location:35 → 221
    G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
    pfam02781
    Location:224 → 511
    G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain

  5. NM_001338867.1 → NP_001325680.1  glucose-6-phosphate dehydrogenase 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VBL3, A0A1I9LLZ7, A0A5S9XG42
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LK23.1

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