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PP2AA2 protein phosphatase 2A subunit A2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822171, updated on 18-Sep-2024

Summary

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Official Symbol
PP2AA2
Official Full Name
protein phosphatase 2A subunit A2
Primary source
TAIR:AT3G25800
Locus tag
AT3G25800
See related
Araport:AT3G25800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
PDF1; PHOSPHATASE 2A REGULATORY SUBUNIT; PR 65; protein phosphatase 2A subunit A2; protein phosphatase 2A subunit A2
Summary
one of three genes encoding the protein phosphatase 2A regulatory subunit
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Genomic context

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See PP2AA2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Sequence:
Chromosome: 3; NC_003074.8 (9422476..9426049, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene myb-like transcription factor family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Terpenoid cyclases/Protein prenyltransferases superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation of cDNA and genomic clones encoding homologues of the 65 kDa regulatory subunit of protein phosphatase 2A in Arabidopsis thaliana. Slabas AR, et al. Plant Mol Biol, 1994 Nov. PMID 7811971
  2. Protein phosphatase 2A holoenzyme is targeted to peroxisomes by piggybacking and positively affects peroxisomal β-oxidation. Kataya AR, et al. Plant Physiol, 2015 Feb. PMID 25489022, Free PMC Article
  3. ROTUNDA3 function in plant development by phosphatase 2A-mediated regulation of auxin transporter recycling. Karampelias M, et al. Proc Natl Acad Sci U S A, 2016 Mar 8. PMID 26888284, Free PMC Article
  4. PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1. Tang W, et al. Nat Cell Biol, 2011 Feb. PMID 21258370, Free PMC Article
  5. The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. Cuéllar Pérez A, et al. PLoS One, 2014. PMID 24416306, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001035692.1
NM_001338767.1
NM_113479.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphatase regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
protein phosphatase 2A subunit A2
NP_001030769.1
  • protein phosphatase 2A subunit A2 (PP2AA2); FUNCTIONS IN: protein phosphatase type 2A regulator activity; INVOLVED IN: response to cadmium ion, regulation of phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A subunit A3 (TAIR:AT1G13320.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_189208.1
  • protein phosphatase 2A subunit A2 (PP2AA2); FUNCTIONS IN: protein phosphatase type 2A regulator activity; INVOLVED IN: response to cadmium ion, regulation of phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A subunit A3 (TAIR:AT1G13320.3); Has 2834 Blast hits to 1736 proteins in 250 species: Archae - 15; Bacteria - 74; Metazoa - 1458; Fungi - 417; Plants - 306; Viruses - 0; Other Eukaryotes - 564 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    9422476..9426049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113479.5 → NP_189208.1  protein phosphatase 2A subunit A2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189208.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38950, Q9LRZ9
    UniProtKB/TrEMBL
    A0A178VIW5, A0A5S9XFL5
    Conserved Domains (2) summary
    COG1413
    Location:196 → 419
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]

  2. NM_001338767.1 → NP_001326959.1  protein phosphatase 2A subunit A2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38950, Q9LRZ9
    UniProtKB/TrEMBL
    A0A178VIW5, A0A5S9XFL5
    Conserved Domains (2) summary
    COG1413
    Location:196 → 419
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]

  3. NM_001035692.1 → NP_001030769.1  protein phosphatase 2A subunit A2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030769.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JA59
    Conserved Domains (5) summary
    COG1413
    Location:43 → 301
    HEAT; HEAT repeat [General function prediction only]
    cd00020
    Location:280 → 378
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam12755
    Location:220 → 300
    Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
    pfam13646
    Location:356 → 461
    HEAT_2; HEAT repeats
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38950.2

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