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CHUP1 Hydroxyproline-rich glycoprotein family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822157, updated on 18-Sep-2024

Summary

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Official Symbol
CHUP1
Official Full Name
Hydroxyproline-rich glycoprotein family protein
Primary source
TAIR:AT3G25690
Locus tag
AT3G25690
See related
Araport:AT3G25690
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
Arabidopsis thaliana CHLOROPLAST UNUSUAL POSITIONING 1; AtCHUP1; CHLOROPLAST UNUSUAL POSITIONING 1
Summary
actin binding protein required for normal chloroplast positioning
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Genomic context

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See CHUP1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Sequence:
Chromosome: 3; NC_003074.8 (9352444..9357953)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene SLH domain protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene basic helix-loop-helix 32

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement. Kong SG, et al. Plant Cell, 2024 Mar 29. PMID 38134410, Free PMC Article
  2. The functional domains of the chloroplast unusual positioning protein 1. Lehmann P, et al. Plant Sci, 2011 Apr. PMID 21421414
  3. The chloroplast outer membrane protein CHUP1 interacts with actin and profilin. Schmidt von Braun S, et al. Planta, 2008 Apr. PMID 18193273
  4. FKF1 Interacts with CHUP1 and Regulates Chloroplast Movement in Arabidopsis. Yuan N, et al. Plants (Basel), 2023 Jan 25. PMID 36771626, Free PMC Article
  5. Light-Induced Movements of Chloroplasts and Nuclei Are Regulated in Both Cp-Actin-Filament-Dependent and -Independent Manners in Arabidopsis thaliana. Suetsugu N, et al. PLoS One, 2016. PMID 27310016, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results indicate that CHUP1 and KAC1/KAC2 function somewhat independently, but interdependently mediate both chloroplast and nuclear photorelocation movements in Arabidopsis cells.
    Title: Light-Induced Movements of Chloroplasts and Nuclei Are Regulated in Both Cp-Actin-Filament-Dependent and -Independent Manners in Arabidopsis thaliana.
  2. CHUP1 functions as a dimer and the leucine zippers in the N-terminal and C-terminal portion of the protein are involved in intramolecular interactions.
    Title: The functional domains of the chloroplast unusual positioning protein 1.
  3. After 5 minutes of exposure to blue light, there were significant differences in expression patterns in phot1 and phot2 mutants from that of the chup1 mutant.
    Title: Transitions of gene expression induced by short-term blue light.
  4. Under high light conditions, chup1 plants assumed significantly different guard cell chloroplast positions on both leaf surfaces than WT plants.
    Title: Light, genotype, and abscisic acid affect chloroplast positioning in guard cells of Arabidopsis thaliana leaves in distinct ways.
  5. CHUP1 localizes on the outer envelope of chloroplasts and anchors chloroplasts to the plasma membrane, forming a bridge to the actin cytoskeleton.
    Title: Chloroplast outer envelope protein CHUP1 is essential for chloroplast anchorage to the plasma membrane and chloroplast movement.
  6. Data show that CHUP1 as a linker between chloroplasts and the cytoskeleton, by interacting with actin and profilin.
    Title: The chloroplast outer membrane protein CHUP1 interacts with actin and profilin.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001203046.1
NM_113468.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables actin filament binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables profilin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament polymerization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within chloroplast relocation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Hydroxyproline-rich glycoprotein family protein
NP_001189974.1
  • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1).
NP_001189975.1
  • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1).
NP_189197.2
  • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); INVOLVED IN: chloroplast relocation; LOCATED IN: chloroplast outer membrane, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1); Has 95745 Blast hits to 54491 proteins in 2679 species: Archae - 1109; Bacteria - 12651; Metazoa - 43667; Fungi - 7750; Plants - 7740; Viruses - 1623; Other Eukaryotes - 21205 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    9352444..9357953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001338761.1 → NP_001327702.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LT47, Q9LI74
    UniProtKB/TrEMBL
    A0A178V7X6
    Conserved Domains (2) summary
    pfam10211
    Location:252 → 336
    Ax_dynein_light; Axonemal dynein light chain
    cl17182
    Location:80 → 230
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

  2. NM_001338762.1 → NP_001327703.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V7X6, A0A1I9LT48

  3. NM_001338763.1 → NP_001327701.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LT47, Q9LI74
    UniProtKB/TrEMBL
    A0A178V7X6
    Conserved Domains (2) summary
    pfam10211
    Location:252 → 336
    Ax_dynein_light; Axonemal dynein light chain
    cl17182
    Location:80 → 230
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

  4. NM_001203045.1 → NP_001189974.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189974.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LT47, Q9LI74
    UniProtKB/TrEMBL
    A0A178V7X6
    Conserved Domains (2) summary
    pfam10211
    Location:252 → 336
    Ax_dynein_light; Axonemal dynein light chain
    cl17182
    Location:80 → 230
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

  5. NM_001203046.1 → NP_001189975.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189975.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V7X6, F4JA42
    Conserved Domains (2) summary
    pfam10211
    Location:111 → 195
    Ax_dynein_light; Axonemal dynein light chain
    pfam16046
    Location:22 → 150
    FAM76; FAM76 protein

  6. NM_113468.5 → NP_189197.2  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189197.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A1I9LT47, Q9LI74
    UniProtKB/TrEMBL
    A0A178V7X6
    Conserved Domains (2) summary
    pfam10211
    Location:252 → 336
    Ax_dynein_light; Axonemal dynein light chain
    cl17182
    Location:80 → 230
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LI74.1

Gene LinkOut

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