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GAE6 UDP-D-glucuronate 4-epimerase 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821965, updated on 18-Sep-2024

Summary

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Official Symbol
GAE6
Official Full Name
UDP-D-glucuronate 4-epimerase 6
Primary source
TAIR:AT3G23820
Locus tag
AT3G23820
See related
Araport:AT3G23820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
UDP-D-glucuronate 4-epimerase 6
Summary
UDP-D-glucuronate 4-epimerase
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Genomic context

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See GAE6 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_003074.8 (8603212..8605810)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-l-homocysteine (SAH) hydrolase 2 Neighboring gene ncRNA Neighboring gene glycine-rich RNA-binding protein 4 Neighboring gene HXXXD-type acyl-transferase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pectin Biosynthesis Is Critical for Cell Wall Integrity and Immunity in Arabidopsis thaliana. Bethke G, et al. Plant Cell, 2016 Feb. PMID 26813622, Free PMC Article
  2. The biosynthesis of D-Galacturonate in plants. functional cloning and characterization of a membrane-anchored UDP-D-Glucuronate 4-epimerase from Arabidopsis. Mølhøj M, et al. Plant Physiol, 2004 Jul. PMID 15247385, Free PMC Article
  3. Identification of proteins that interact with catalytically active calcium-dependent protein kinases from Arabidopsis. Uno Y, et al. Mol Genet Genomics, 2009 Apr. PMID 19130088
  4. Label-free protein quantification for plant Golgi protein localization and abundance. Nikolovski N, et al. Plant Physiol, 2014 Oct. PMID 25122472, Free PMC Article
  5. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_113287.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables UDP-glucuronate 4-epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glucuronate 4-epimerase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to Gram-negative bacterium IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within defense response to fungus IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within galacturonate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in Golgi trans cisterna HDA PubMed 
located_in endosome HDA PubMed 
located_in trans-Golgi network HDA PubMed 

General protein information

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Preferred Names
UDP-D-glucuronate 4-epimerase 6
NP_189024.1
  • UDP-D-glucuronate 4-epimerase 6 (GAE6); FUNCTIONS IN: UDP-glucuronate 4-epimerase activity, catalytic activity; INVOLVED IN: cellular metabolic process, carbohydrate metabolic process, nucleotide-sugar metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), Nucleotide sugar epimerase (InterPro:IPR008089); BEST Arabidopsis thaliana protein match is: UDP-D-glucuronate 4-epimerase 2 (TAIR:AT1G02000.1); Has 39778 Blast hits to 39772 proteins in 2962 species: Archae - 777; Bacteria - 23781; Metazoa - 723; Fungi - 392; Plants - 1153; Viruses - 36; Other Eukaryotes - 12916 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8603212..8605810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113287.3 → NP_189024.1  UDP-D-glucuronate 4-epimerase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189024.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8H7G2, Q9LIS3
    UniProtKB/TrEMBL
    A0A178VKU1, A0A384LE13, I1VCA6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LIS3.1

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