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DSPTP1 dual specificity protein phosphatase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821941, updated on 18-Sep-2024

Summary

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Official Symbol
DSPTP1
Official Full Name
dual specificity protein phosphatase 1
Primary source
TAIR:AT3G23610
Locus tag
AT3G23610
See related
Araport:AT3G23610
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
dual specificity protein phosphatase 1
Summary
Encodes a dual specificity protein phosphatase whose activity is modulated by CaM binding.
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Genomic context

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See DSPTP1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (8477800..8479877)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like superfamily protein Neighboring gene ncRNA Neighboring gene Ribosomal RNA processing Brix domain protein Neighboring gene isopentenyltransferase 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AtDsPTP1 acts as a negative regulator in osmotic stress signalling during Arabidopsis seed germination and seedling establishment. Liu R, et al. J Exp Bot, 2015 Mar. PMID 25540435, Free PMC Article
  2. Identification of a dual-specificity protein phosphatase that inactivates a MAP kinase from Arabidopsis. Gupta R, et al. Plant J, 1998 Dec. PMID 10036776
  3. Regulation of the dual specificity protein phosphatase, DsPTP1, through interactions with calmodulin. Yoo JH, et al. J Biol Chem, 2004 Jan 9. PMID 14570888
  4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DsPTP1 acts as a negative regulator in osmotic stress signalling during seed germination and seedling growth.
    Title: AtDsPTP1 acts as a negative regulator in osmotic stress signalling during Arabidopsis seed germination and seedling establishment.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001125211.3
NM_001203026.1
NM_001338651.1
NM_113265.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calmodulin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine/serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
NOT involved_in cellular response to cold NAS
Non-traceable Author Statement
more info
 PubMed 
NOT involved_in cellular response to heat NAS
Non-traceable Author Statement
more info
 PubMed 
NOT involved_in cellular response to salt stress NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
NOT involved_in response to wounding NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
dual specificity protein phosphatase 1
NP_001118683.1
  • dual specificity protein phosphatase 1 (DSPTP1); CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase (InterPro:IPR020417), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: MAPK phosphatase 2 (TAIR:AT3G06110.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001189955.1
  • dual specificity protein phosphatase 1 (DSPTP1); CONTAINS InterPro DOMAIN/s: Dual specificity phosphatase (InterPro:IPR020417), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: MAPK phosphatase 2 (TAIR:AT3G06110.3).
NP_189003.1
  • dual specificity protein phosphatase 1 (DSPTP1); CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase (InterPro:IPR020417), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: MAPK phosphatase 2 (TAIR:AT3G06110.3); Has 4429 Blast hits to 4425 proteins in 398 species: Archae - 22; Bacteria - 149; Metazoa - 2258; Fungi - 464; Plants - 388; Viruses - 233; Other Eukaryotes - 915 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    8477800..8479877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001338649.1 → NP_001326887.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LQM6, A0A5S9XF87, A0A654FA08
    Conserved Domains (1) summary
    cd14498
    Location:51 → 184
    DSP; dual-specificity phosphatase domain

  2. NM_001338650.1 → NP_001326888.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LQM7, A0A5S9XF87, A0A654FA08

  3. NM_001125211.3 → NP_001118683.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001118683.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XF87, A0A654FA08
    Conserved Domains (1) summary
    cd14498
    Location:51 → 184
    DSP; dual-specificity phosphatase domain

  4. NM_001338651.1 → NP_001326889.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LQM8

  5. NM_113265.1 → NP_189003.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189003.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3H4F5, F4J449, Q9LUG6, Q9ZR37
    UniProtKB/TrEMBL
    A0A5S9XF87, A0A654FA08
    Conserved Domains (1) summary
    cd14498
    Location:51 → 184
    DSP; dual-specificity phosphatase domain

  6. NM_001203026.1 → NP_001189955.1  dual specificity protein phosphatase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189955.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XF87, A0A654FA08
    Conserved Domains (2) summary
    COG2453
    Location:53 → 191
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    cd00127
    Location:51 → 186
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZR37.1

Gene LinkOut

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