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AOX1A alternative oxidase 1A [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821806, updated on 18-Sep-2024

Summary

Official Symbol
AOX1A
Official Full Name
alternative oxidase 1A
Primary source
TAIR:AT3G22370
Locus tag
AT3G22370
See related
Araport:AT3G22370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alternative oxidase 1A; ATAOX1A; AtHSR3; HSR3; hyper-sensitivity-related 3
Summary
Encodes AOX1a, an isoform of alternative oxidase that is expressed in rosettes, flowers, and root. The alternative oxidase of plant mitochondria transfers electrons from the ubiquinone pool to oxygen without energy conservations. It is regulated through transcriptional control and by pyruvate. Plays a role in shoot acclimation to low temperature. Also is capable of ameliorating reactive oxygen species production when the cytochrome pathway is inhibited. AOX1a also functions as a marker for mitochondrial retrograde response.
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Genomic context

See AOX1A in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (7906521..7908746)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene alternative oxidase 1B Neighboring gene time for coffee Neighboring gene PLAT/LH2 domain-containing lipoxygenase family protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
alternative oxidase 1A
NP_188876.1
  • alternative oxidase 1A (AOX1A); FUNCTIONS IN: alternative oxidase activity; INVOLVED IN: oxidation reduction, cellular respiration, response to cold, response to stress, mitochondria-nucleus signaling pathway; LOCATED IN: mitochondrion; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Alternative oxidase (InterPro:IPR002680); BEST Arabidopsis thaliana protein match is: alternative oxidase 1B (TAIR:AT3G22360.1); Has 1299 Blast hits to 1299 proteins in 245 species: Archae - 0; Bacteria - 109; Metazoa - 12; Fungi - 194; Plants - 380; Viruses - 0; Other Eukaryotes - 604 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    7906521..7908746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_113135.4NP_188876.1  alternative oxidase 1A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188876.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23914, P93734, Q39219, Q9ZRT8
    UniProtKB/TrEMBL
    A0A178V8B9, A0A5S9XEJ9, A0A654FAW8
    Conserved Domains (1) summary
    PLN02478
    Location:23354
    PLN02478; alternative oxidase