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EIN3 Ethylene insensitive 3 family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821625, updated on 18-Sep-2024

Summary

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Official Symbol
EIN3
Official Full Name
Ethylene insensitive 3 family protein
Primary source
TAIR:AT3G20770
Locus tag
AT3G20770
See related
Araport:AT3G20770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtEIN3; ETHYLENE-INSENSITIVE3
Summary
Encodes EIN3 (ethylene-insensitive3), a nuclear transcription factor that initiates downstream transcriptional cascades for ethylene responses.
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Genomic context

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See EIN3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
2
Sequence:
Chromosome: 3; NC_003074.8 (7260429..7263384, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene GATA transcription factor 29 Neighboring gene Nse4, component of Smc5/6 DNA repair complex Neighboring gene topoisomerase 6 subunit B Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enhanced oxidative stress in the ethylene-insensitive (ein3-1) mutant of Arabidopsis thaliana exposed to salt stress. Asensi-Fabado MA, et al. J Plant Physiol, 2012 Mar 1. PMID 22209220
  2. Ethylene signaling cross-talk with other hormones in Arabidopsis thaliana exposed to contrasting phosphate availability: Differential effects in roots, leaves and fruits. Munné-Bosch S, et al. J Plant Physiol, 2018 Jul. PMID 29758376
  3. Allosteric deactivation of PIFs and EIN3 by microproteins in light control of plant development. Wu Q, et al. Proc Natl Acad Sci U S A, 2020 Aug 4. PMID 32694206, Free PMC Article
  4. The Arabidopsis AMOT1/EIN3 gene plays an important role in the amelioration of ammonium toxicity. Li G, et al. J Exp Bot, 2019 Feb 20. PMID 30689938, Free PMC Article
  5. Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. Chang KN, et al. Elife, 2013 Jun 11. PMID 23795294, Free PMC Article

See all (65) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ETHYLENE INSENSITIVE3/EIN3-LIKE1 modulate FLOWERING LOCUS C expression via histone demethylase interaction.
    Title: ETHYLENE INSENSITIVE3/EIN3-LIKE1 modulate FLOWERING LOCUS C expression via histone demethylase interaction.
  2. EIN3 and RSL4 interfere with an MYB-bHLH-WD40 complex to mediate ethylene-induced ectopic root hair formation in Arabidopsis.
    Title: EIN3 and RSL4 interfere with an MYB-bHLH-WD40 complex to mediate ethylene-induced ectopic root hair formation in Arabidopsis.
  3. MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis.
    Title: MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis.
  4. EIN3-Mediated Ethylene Signaling Attenuates Auxin Response during Hypocotyl Thermomorphogenesis.
    Title: EIN3-Mediated Ethylene Signaling Attenuates Auxin Response during Hypocotyl Thermomorphogenesis.
  5. MYB30 and ETHYLENE INSENSITIVE3 antagonistically modulate root hair growth in Arabidopsis.
    Title: MYB30 and ETHYLENE INSENSITIVE3 antagonistically modulate root hair growth in Arabidopsis.
  6. EIN2-directed histone acetylation requires EIN3-mediated positive feedback regulation in response to ethylene.
    Title: EIN2-directed histone acetylation requires EIN3-mediated positive feedback regulation in response to ethylene.
  7. The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis.
    Title: The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis.
  8. TREE1-EIN3-mediated transcriptional repression inhibits shoot growth in response to ethylene.
    Title: TREE1-EIN3-mediated transcriptional repression inhibits shoot growth in response to ethylene.
  9. Salicylic Acid Suppresses Apical Hook Formation via NPR1-Mediated Repression of EIN3 and EIL1 in Arabidopsis.
    Title: Salicylic Acid Suppresses Apical Hook Formation via NPR1-Mediated Repression of EIN3 and EIL1 in Arabidopsis.
  10. Allosteric deactivation of PIFs and EIN3 by microproteins in light control of plant development.
    Title: Allosteric deactivation of PIFs and EIN3 by microproteins in light control of plant development.
Submit: New GeneRIF Correction See all GeneRIFs (44)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_112968.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
 PubMed 
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to bacterium IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in epigenetic regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within ethylene-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ethylene-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within ethylene-activated signaling pathway TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within regulation of L-ascorbic acid biosynthetic process IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to ethylene IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to hypoxia IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sugar mediated signaling pathway TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in nucleus TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
Ethylene insensitive 3 family protein
NP_188713.1
  • ETHYLENE-INSENSITIVE3 (EIN3); CONTAINS InterPro DOMAIN/s: Ethylene insensitive 3 (InterPro:IPR006957); BEST Arabidopsis thaliana protein match is: ETHYLENE-INSENSITIVE3-like 1 (TAIR:AT2G27050.1); Has 12681 Blast hits to 4386 proteins in 108 species: Archae - 12; Bacteria - 9; Metazoa - 78; Fungi - 631; Plants - 331; Viruses - 0; Other Eukaryotes - 11620 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    7260429..7263384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112968.4 → NP_188713.1  Ethylene insensitive 3 family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188713.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O24606, Q8VYW4
    UniProtKB/TrEMBL
    A0A178VGP6, A0A5S9XEH1
    Conserved Domains (1) summary
    pfam04873
    Location:49 → 296
    EIN3; Ethylene insensitive 3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O24606.1

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