CFM2 CRM family member 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CFM2
Official Full Name: CRM family member 2
Primary source: TAIR:AT3G01370
Locus tag: AT3G01370
See related: Araport:AT3G01370
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Arabidopsis thaliana CRM family member 2; ATCFM2; CRM family member 2; T13O15.1; T13O15_1
Summary: Encodes a protein containing a CRM domain that is involved in group I and group II intron splicing.
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Genomic context

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See CFM2 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 13

Sequence:: Chromosome: 3; NC_003074.8 (139011..143782)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group II introns in Arabidopsis chloroplasts.
Title: The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group II introns in Arabidopsis chloroplasts.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_111003.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within Group I intron splicing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within Group II intron splicing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info	PubMed
located_in plastid stroma	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: CRM family member 2

NP_186786.2

CRM family member 2 (CFM2); FUNCTIONS IN: RNA binding; INVOLVED IN: Group I intron splicing, Group II intron splicing; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA-binding, CRM domain (InterPro:IPR001890); BEST Arabidopsis thaliana protein match is: CRM family member 3B (TAIR:AT4G14510.1); Has 1269 Blast hits to 881 proteins in 154 species: Archae - 0; Bacteria - 46; Metazoa - 247; Fungi - 72; Plants - 683; Viruses - 4; Other Eukaryotes - 217 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

139011..143782

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_111003.5 → NP_186786.2 CRM family member 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_186786.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8L7C2, Q9SGI0

UniProtKB/TrEMBL

A0A178VGM9, A0A5S9X873, A0A654F342

Conserved Domains (2) summary

smart01103
Location:579 → 666

CRS1_YhbY; Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly

pfam01985
Location:169 → 249

CRS1_YhbY; CRS1 / YhbY (CRM) domain