U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NPC3 non-specific phospholipase C3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821244, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
NPC3
Official Full Name
non-specific phospholipase C3
Primary source
TAIR:AT3G03520
Locus tag
AT3G03520
See related
Araport:AT3G03520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
non-specific phospholipase C3; T21P5.6; T21P5_6
Summary
Lysophosphatidic acid phosphatase highly expressed during phosphate starvation and abiotic stresses. Role in lipid synthesis.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NPC3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (837805..840645, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene non-specific phospholipase C4 Neighboring gene non-specific phospholipase C5

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional characterization of lysophosphatidic acid phosphatase from Arabidopsis thaliana. Reddy VS, et al. Biochim Biophys Acta, 2010 Apr. PMID 20045079
  2. Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis. Li T, et al. Plant Cell, 2024 May 29. PMID 38442314,
  3. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
  4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
  5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis.
    Title: Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001337474.1
NM_111223.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lysophosphatidic acid phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
NOT enables phospholipase C activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to phosphate starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within phosphate-containing compound metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
located_in plasmodesma HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
non-specific phospholipase C3
NP_187002.1
  • non-specific phospholipase C3 (NPC3); FUNCTIONS IN: hydrolase activity, acting on ester bonds, Lysophosphatidic acid phosphatase activity; INVOLVED IN: cellular response to phosphate starvation, phosphate metabolic process, response to abiotic stimulus; LOCATED IN: vacuole, membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoesterase (InterPro:IPR007312); BEST Arabidopsis thaliana protein match is: non-specific phospholipase C4 (TAIR:AT3G03530.1); Has 2235 Blast hits to 2112 proteins in 404 species: Archae - 32; Bacteria - 1866; Metazoa - 0; Fungi - 127; Plants - 159; Viruses - 0; Other Eukaryotes - 51 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    837805..840645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111223.5 → NP_187002.1  non-specific phospholipase C3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187002.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VZ53, Q9SRQ6
    UniProtKB/TrEMBL
    A0A178VBD6, A0A5S9X915
    Conserved Domains (1) summary
    pfam04185
    Location:16 → 381
    Phosphoesterase; Phosphoesterase family

  2. NM_001337474.1 → NP_001326666.1  non-specific phospholipase C3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LPZ5
    Conserved Domains (1) summary
    pfam04185
    Location:16 → 381
    Phosphoesterase; Phosphoesterase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SRQ6.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools