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DEL3 DP-E2F-like protein 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821221, updated on 18-Sep-2024

Summary

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Official Symbol
DEL3
Official Full Name
DP-E2F-like protein 3
Primary source
TAIR:AT3G01330
Locus tag
AT3G01330
See related
Araport:AT3G01330
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DP-E2F-like protein 3; DP-E2F-LIKE PROTEIN 3; E2F-LIKE 2; E2FF; E2L2; T22N4.4; T22N4_4
Summary
Member of the E2F transcription factors, (cell cycle genes), key components of the cyclin D/retinoblastoma/E2F pathway.
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Genomic context

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See DEL3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Sequence:
Chromosome: 3; NC_003074.8 (124319..126876, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ECA1-like gametogenesis related family protein Neighboring gene uncharacterized protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. E2Ls, E2F-like repressors of Arabidopsis that bind to E2F sites in a monomeric form. Kosugi S, et al. J Biol Chem, 2002 May 10. PMID 11867638
  2. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article
  3. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
  4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
  5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_110999.7

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DP-E2F-like protein 3
NP_186782.2
  • DP-E2F-like protein 3 (DEL3); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: DP-E2F-like 2 (TAIR:AT5G14960.1); Has 1046 Blast hits to 870 proteins in 117 species: Archae - 0; Bacteria - 4; Metazoa - 638; Fungi - 7; Plants - 262; Viruses - 0; Other Eukaryotes - 135 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    124319..126876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_110999.7 → NP_186782.2  DP-E2F-like protein 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_186782.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8RWL0, Q9SRI0
    UniProtKB/TrEMBL
    A0A178V7U8, A0A5S9X843, A0A7G2EK81
    Conserved Domains (1) summary
    pfam02319
    Location:23 → 86
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8RWL0.1

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