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SKOR STELAR K+ outward rectifier [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821052, updated on 18-Sep-2024

Summary

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Official Symbol
SKOR
Official Full Name
STELAR K+ outward rectifier
Primary source
TAIR:AT3G02850
Locus tag
AT3G02850
See related
Araport:AT3G02850
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F13E7.21; F13E7_21; STELAR K+ outward rectifier
Summary
Encodes SKOR, a member of Shaker family potassium ion (K+) channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). Mediates the delivery of K+ from stelar cells to the xylem in the roots towards the shoot. mRNA accumulation is modulated by abscisic acid. K+ gating activity is modulated by external and internal K+.
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Genomic context

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See SKOR in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Sequence:
Chromosome: 3; NC_003074.8 (619678..623739, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ARM repeat superfamily protein Neighboring gene ncRNA Neighboring gene zinc ion binding protein Neighboring gene Inositol monophosphatase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A minimal cysteine motif required to activate the SKOR K+ channel of Arabidopsis by the reactive oxygen species H2O2. Garcia-Mata C, et al. J Biol Chem, 2010 Sep 17. PMID 20605786, Free PMC Article
  2. Single mutations convert an outward K+ channel into an inward K+ channel. Li L, et al. Proc Natl Acad Sci U S A, 2008 Feb 26. PMID 18287042, Free PMC Article
  3. External K+ modulates the activity of the Arabidopsis potassium channel SKOR via an unusual mechanism. Johansson I, et al. Plant J, 2006 Apr. PMID 16623889
  4. Intracellular K+ sensing of SKOR, a Shaker-type K+ channel from Arabidopsis. Liu K, et al. Plant J, 2006 Apr. PMID 16623888
  5. Identification and disruption of a plant shaker-like outward channel involved in K+ release into the xylem sap. Gaymard F, et al. Cell, 1998 Sep 4. PMID 9741629

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that nutritional conditions as a critical factor for the joint activity of Arabidopsis proteins SKOR and NPF7.3/NRT1.5 for shoot potassium (K) homeostasis.
    Title: Nitrate-Dependent Control of Shoot K Homeostasis by the Nitrate Transporter1/Peptide Transporter Family Member NPF7.3/NRT1.5 and the Stelar K+ Outward Rectifier SKOR in Arabidopsis.
  2. Study found that, in particular, the N-terminal part of the S5 played a critical role in KAT1 and SKOR gating.
    Title: Distributed structures underlie gating differences between the kin channel KAT1 and the Kout channel SKOR.
  3. A minimal cysteine motif required to activate the SKOR K+ channel of Arabidopsis by the reactive oxygen species H2O2.
    Title: A minimal cysteine motif required to activate the SKOR K+ channel of Arabidopsis by the reactive oxygen species H2O2.
  4. Single mutations in SKOR convert it from an outward K+ channel into an inward K+ channel.
    Title: Single mutations convert an outward K+ channel into an inward K+ channel.
  5. Mapping the SKOR sequence to the crystal structure of the voltage-dependent K+ channel suggests interaction between the S6 gating domain and the base of the pore helix, a prediction supported by mutations at this site.
    Title: External K+ modulates the activity of the Arabidopsis potassium channel SKOR via an unusual mechanism.
  6. The intracellular potassium sensing mechanism couples SKOR activity to potassium nutrition status in the 'source cells', establishing a supply-based unloading system for the regulation of potassium distribution.
    Title: Intracellular K+ sensing of SKOR, a Shaker-type K+ channel from Arabidopsis.
  7. Phosphatidylinositol phosphates were identified as essential regulators for the voltage-dependent and -independent activation of A. thaliana potassium channels expressed in X. laevis oocytes.
    Title: An essential function of phosphatidylinositol phosphates in activation of plant shaker-type K+ channels.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001337437.1
NM_001337438.1
NM_111153.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
NOT enables inward rectifier potassium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables outward rectifier potassium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within potassium ion homeostasis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within potassium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within potassium ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within potassium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
STELAR K+ outward rectifier
NP_186934.1
  • STELAR K+ outward rectifier (SKOR); FUNCTIONS IN: outward rectifier potassium channel activity, cyclic nucleotide binding; INVOLVED IN: potassium ion transport, response to abscisic acid stimulus; LOCATED IN: membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Potassium channel, voltage-dependent, EAG/ELK/ERG (InterPro:IPR003938), Protein of unknown function DUF3354 (InterPro:IPR021789), Ankyrin repeat-containing domain (InterPro:IPR020683), Ion transport (InterPro:IPR005821), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: gated outwardly-rectifying K+ channel (TAIR:AT5G37500.1); Has 82938 Blast hits to 34972 proteins in 1815 species: Archae - 147; Bacteria - 10317; Metazoa - 39460; Fungi - 7131; Plants - 3765; Viruses - 1138; Other Eukaryotes - 20980 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    619678..623739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111153.4 → NP_186934.1  STELAR K+ outward rectifier [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_186934.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82630, Q9M8S6, Q9SB86
    UniProtKB/TrEMBL
    A0A178VHK5, A0A5S9X8K2
    Conserved Domains (2) summary
    PLN03192
    Location:70 → 827
    PLN03192; Voltage-dependent potassium channel; Provisional
    sd00045
    Location:580 → 611
    ANK; ANK repeat [structural motif]

  2. NM_001337437.1 → NP_001325630.1  STELAR K+ outward rectifier [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LLU1

  3. NM_001337438.1 → NP_001325629.1  STELAR K+ outward rectifier [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LLU0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M8S6.1

Gene LinkOut

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