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WSIP2 WUS-interacting protein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820831, updated on 18-Sep-2024

Summary

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Official Symbol
WSIP2
Official Full Name
WUS-interacting protein 2
Primary source
TAIR:AT3G15880
Locus tag
AT3G15880
See related
Araport:AT3G15880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
TOPLESS-RELATED 4; TPR4; WUS-interacting protein 2
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Genomic context

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See WSIP2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
27
Sequence:
Chromosome: 3; NC_003074.8 (5364081..5372293, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene fatty acid desaturase 5 Neighboring gene plant self-incompatibility protein S1 family protein Neighboring gene Fatty acid desaturase family protein Neighboring gene Protein kinase superfamily protein Neighboring gene homoserine O-acetyltransferase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance. Kieffer M, et al. Plant Cell, 2006 Mar. PMID 16461579, Free PMC Article
  2. TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1. Oh E, et al. Nat Commun, 2014 Jun 18. PMID 24938363, Free PMC Article
  3. TOPLESS regulates apical embryonic fate in Arabidopsis. Long JA, et al. Science, 2006 Jun 9. PMID 16763149
  4. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Fukazawa J, et al. Plant Cell, 2014 Jul. PMID 25035403, Free PMC Article
  5. The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis ovule development. Wei B, et al. Cell Res, 2015 Jan. PMID 25378179, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001202976.1
NM_001338190.1
NM_112458.5
NM_180672.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in gibberellic acid homeostasis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of gibberellic acid mediated signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within primary shoot apical meristem specification IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
WUS-interacting protein 2
NP_001189905.1
  • WUS-interacting protein 2 (WSIP2); FUNCTIONS IN: protein binding; INVOLVED IN: primary shoot apical meristem specification; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT1G15750.4).
NP_188209.3
  • WUS-interacting protein 2 (WSIP2); FUNCTIONS IN: protein binding; INVOLVED IN: primary shoot apical meristem specification; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT1G15750.4); Has 22596 Blast hits to 13790 proteins in 615 species: Archae - 20; Bacteria - 4432; Metazoa - 7625; Fungi - 4980; Plants - 2394; Viruses - 0; Other Eukaryotes - 3145 (source: NCBI BLink).
NP_851003.2
  • WUS-interacting protein 2 (WSIP2); FUNCTIONS IN: protein binding; INVOLVED IN: primary shoot apical meristem specification; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT1G15750.4); Has 22632 Blast hits to 13797 proteins in 616 species: Archae - 20; Bacteria - 4458; Metazoa - 7628; Fungi - 4973; Plants - 2405; Viruses - 0; Other Eukaryotes - 3148 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    5364081..5372293 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112458.5 → NP_188209.3  WUS-interacting protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188209.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XCI3
    Conserved Domains (5) summary
    smart00667
    Location:4 → 34
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:34 → 92
    CTLH; C-terminal to LisH motif
    COG2319
    Location:361 → 967
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:360 → 417
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:349 → 669
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_180672.4 → NP_851003.2  WUS-interacting protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851003.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DHS5, Q0WMG2, Q27GK7, Q3EB60, Q9LVZ2
    UniProtKB/TrEMBL
    A0A178VJ72, A0A5S9XCI3
    Conserved Domains (4) summary
    smart00667
    Location:4 → 34
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:34 → 92
    CTLH; C-terminal to LisH motif
    sd00039
    Location:362 → 417
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:349 → 669
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_001202976.1 → NP_001189905.1  WUS-interacting protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189905.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XCI3, F4J043
    Conserved Domains (5) summary
    smart00667
    Location:4 → 34
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:34 → 92
    CTLH; C-terminal to LisH motif
    COG2319
    Location:361 → 957
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:362 → 417
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:349 → 659
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. NM_001338190.1 → NP_001325883.1  WUS-interacting protein 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DHS5, Q0WMG2, Q27GK7, Q3EB60, Q9LVZ2
    UniProtKB/TrEMBL
    A0A178VJ72, A0A5S9XCI3
    Conserved Domains (4) summary
    smart00667
    Location:4 → 34
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:34 → 92
    CTLH; C-terminal to LisH motif
    sd00039
    Location:362 → 417
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:349 → 669
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27GK7.2

Gene LinkOut

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