TBP1 TATA binding protein 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: TBP1
Official Full Name: TATA binding protein 1
Primary source: TAIR:AT3G13445
Locus tag: AT3G13445
See related: Araport:AT3G13445
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: TATA binding protein 1; TFIID-1; TRANSCRIPTION FACTOR IID-1
Summary: TBP (TATA binding protein) associates with TAF(II)s (TBP-associated factors) to form the TFIID general transcription factor complex
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Genomic context

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See TBP1 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 9

Sequence:: Chromosome: 3; NC_003074.8 (4379793..4382224)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis Pol II is indispensable for endogenous siRNA-mediated transcriptional gene silencing (TGS) at intergenic low-copy-number loci, despite the presence of two other polymerases-Pol IV and Pol V-that specialize in TGS through siRNAs
Title: Intergenic transcription by RNA polymerase II coordinates Pol IV and Pol V in siRNA-directed transcriptional gene silencing in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001035611.2

Supported by ESTs:

NM_112190.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: TATA binding protein 1

NP_001030688.1

TATA binding protein 1 (TBP1); FUNCTIONS IN: RNA polymerase II transcription factor activity, binding, DNA binding; INVOLVED IN: transcription initiation from RNA polymerase II promoter, regulation of transcription, DNA-dependent; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA-box binding (InterPro:IPR000814), Beta2-adaptin/TATA-box binding, C-terminal (InterPro:IPR012295), Transcription factor TFIID, C-terminal/DNA glycosylase, N-terminal (InterPro:IPR012294); BEST Arabidopsis thaliana protein match is: TATA binding protein 2 (TAIR:AT1G55520.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_187953.1

TATA binding protein 1 (TBP1); FUNCTIONS IN: RNA polymerase II transcription factor activity, binding, DNA binding; INVOLVED IN: transcription initiation from RNA polymerase II promoter, regulation of transcription, DNA-dependent; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA-box binding (InterPro:IPR000814), Beta2-adaptin/TATA-box binding, C-terminal (InterPro:IPR012295), Transcription factor TFIID, C-terminal/DNA glycosylase, N-terminal (InterPro:IPR012294); BEST Arabidopsis thaliana protein match is: TATA binding protein 2 (TAIR:AT1G55520.2); Has 2082 Blast hits to 1578 proteins in 405 species: Archae - 722; Bacteria - 0; Metazoa - 573; Fungi - 191; Plants - 155; Viruses - 0; Other Eukaryotes - 441 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

4379793..4382224

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112190.5 → NP_187953.1 TATA binding protein 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_187953.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P28147, Q53YT8

UniProtKB/TrEMBL

A0A5S9XBZ5, A0A654FC19

Conserved Domains (1) summary

PLN00062
Location:22 → 200

PLN00062; TATA-box-binding protein; Provisional
NM_001035611.2 → NP_001030688.1 TATA binding protein 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001030688.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V930, A0A384KWS0, F4JDC0

Conserved Domains (2) summary

PLN00062
Location:22 → 193

PLN00062; TATA-box-binding protein; Provisional

cd04516
Location:22 → 188

TBP_eukaryotes; eukaryotic TATA box binding protein (TBP): Present in archaea and eukaryotes, TBPs are transcription factors that recognize promoters and initiate transcription. TBP has been shown to be an essential component of three different transcription initiation ...