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WIP3 WPP domain interacting protein 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820536, updated on 18-Sep-2024

Summary

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Official Symbol
WIP3
Official Full Name
WPP domain interacting protein 3
Primary source
TAIR:AT3G13360
Locus tag
AT3G13360
See related
Araport:AT3G13360
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
WPP domain interacting protein 3
Summary
Encodes an outer nuclear membrane protein that anchors RanGAP1 to the nuclear envelope. It interacts with SUN proteins and is required for maintaining the elongated nuclear shape of epidermal cells.
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Genomic context

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See WIP3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (4338250..4340446, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain-containing protein Neighboring gene formin-like protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins. Xu XM, et al. Curr Biol, 2007 Jul 3. PMID 17600715
  2. SUN anchors pollen WIP-WIT complexes at the vegetative nuclear envelope and is necessary for pollen tube targeting and fertility. Zhou X, et al. J Exp Bot, 2015 Dec. PMID 26409047, Free PMC Article
  3. Novel plant SUN-KASH bridges are involved in RanGAP anchoring and nuclear shape determination. Zhou X, et al. J Cell Biol, 2012 Jan 23. PMID 22270916, Free PMC Article
  4. Plant nuclear shape is independently determined by the SUN-WIP-WIT2-myosin XI-i complex and CRWN1. Zhou X, et al. Nucleus, 2015. PMID 25759303, Free PMC Article
  5. The TOPLESS interactome: a framework for gene repression in Arabidopsis. Causier B, et al. Plant Physiol, 2012 Jan. PMID 22065421, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001338045.1
NM_112181.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within nucleus organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
WPP domain interacting protein 3
NP_566455.1
  • WPP domain interacting protein 3 (WIP3); BEST Arabidopsis thaliana protein match is: WPP domain interacting protein 1 (TAIR:AT4G26455.1); Has 169 Blast hits to 165 proteins in 48 species: Archae - 0; Bacteria - 16; Metazoa - 21; Fungi - 13; Plants - 65; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4338250..4340446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112181.5 → NP_566455.1  WPP domain interacting protein 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566455.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94AV5, Q9LTT2
    UniProtKB/TrEMBL
    A0A178V5S4
    Conserved Domains (1) summary
    COG4717
    Location:250 → 407
    YhaN; Uncharacterized protein YhaN, contains AAA domain [Function unknown]

  2. NM_001338045.1 → NP_001327578.1  WPP domain interacting protein 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LSR4, A0A654F6R3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94AV5.1

Gene LinkOut

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