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CAX2 cation exchanger 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820532, updated on 18-Sep-2024

Summary

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Official Symbol
CAX2
Official Full Name
cation exchanger 2
Primary source
TAIR:AT3G13320
Locus tag
AT3G13320
See related
Araport:AT3G13320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
atcax2; cation exchanger 2; MDC11.19
Summary
low affinity calcium antiporter CAX2
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Genomic context

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See CAX2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Sequence:
Chromosome: 3; NC_003074.8 (4314505..4318487)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene proteasome activating protein 200 Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The vacuolar Ca(2+) transporter CATION EXCHANGER 2 regulates cytosolic calcium homeostasis, hypoxic signaling, and response to flooding in Arabidopsis thaliana. Bakshi A, et al. New Phytol, 2023 Dec. PMID 37743731
  2. Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2. Pittman JK, et al. FEBS Lett, 2005 May 9. PMID 15862304
  3. Phylogenetic relationships within cation transporter families of Arabidopsis. Mäser P, et al. Plant Physiol, 2001 Aug. PMID 11500563, Free PMC Article
  4. CAX1, an H+/Ca2+ antiporter from Arabidopsis. Hirschi KD, et al. Proc Natl Acad Sci U S A, 1996 Aug 6. PMID 8710949, Free PMC Article
  5. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The vacuolar Ca[2+] transporter CATION EXCHANGER 2 regulates cytosolic calcium homeostasis, hypoxic signaling, and response to flooding in Arabidopsis thaliana.
    Title: The vacuolar Ca(2+) transporter CATION EXCHANGER 2 regulates cytosolic calcium homeostasis, hypoxic signaling, and response to flooding in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_112177.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium:monoatomic cation antiporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables calcium:proton antiporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium:proton antiporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cadmium ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within calcium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within calcium ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within manganese ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within metal ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within metal ion transport TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in endomembrane system TAS
Traceable Author Statement
more info
 PubMed 
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vacuole IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
cation exchanger 2
NP_566452.1
  • cation exchanger 2 (CAX2); CONTAINS InterPro DOMAIN/s: Sodium/calcium exchanger membrane region (InterPro:IPR004837), Calcium/proton exchanger superfamily (InterPro:IPR004798), Calcium/proton exchanger (InterPro:IPR004713); BEST Arabidopsis thaliana protein match is: cation exchanger 5 (TAIR:AT1G55730.2); Has 3194 Blast hits to 3028 proteins in 968 species: Archae - 39; Bacteria - 1824; Metazoa - 15; Fungi - 731; Plants - 247; Viruses - 0; Other Eukaryotes - 338 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4314505..4318487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112177.3 → NP_566452.1  cation exchanger 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566452.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q39254, Q944Q1, Q9LTT6
    UniProtKB/TrEMBL
    A0A178VHU2, A0A7G2EM62
    Conserved Domains (1) summary
    TIGR00846
    Location:71 → 431
    caca2; calcium/proton exchanger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q39254.2

Gene LinkOut

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