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RRP45a ribonuclease PH45A [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820485, updated on 18-Sep-2024

Summary

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Official Symbol
RRP45a
Official Full Name
ribonuclease PH45A
Primary source
TAIR:AT3G12990
Locus tag
AT3G12990
See related
Araport:AT3G12990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MGH6.11; ribonuclease PH45A
Summary
Encodes a 3'-5' exoribonucleasely redundant with CER7. Involved in epicuticular wax biosynthesis.
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Genomic context

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See RRP45a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Sequence:
Chromosome: 3; NC_003074.8 (4156054..4158004)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene histone acetyltransferase of the CBP family 5 Neighboring gene miscRNA Neighboring gene ubiquinone biosynthesis protein (Protein of unknown function, DUF547) Neighboring gene hAT transposon superfamily protein Neighboring gene hAT transposon superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A core subunit of the RNA-processing/degrading exosome specifically influences cuticular wax biosynthesis in Arabidopsis. Hooker TS, et al. Plant Cell, 2007 Mar. PMID 17351114, Free PMC Article
  2. The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana. Lange H, et al. PLoS Genet, 2014 Aug. PMID 25144737, Free PMC Article
  3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001202945.2
NM_001338017.1
NM_001338018.1
NM_112136.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables 3'-5'-RNA exonuclease activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within wax biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
part_of exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ribonuclease PH45A
NP_001189874.1
  • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3).
NP_001319535.1
  • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_566441.1
  • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3); Has 1192 Blast hits to 1192 proteins in 317 species: Archae - 241; Bacteria - 12; Metazoa - 352; Fungi - 188; Plants - 158; Viruses - 0; Other Eukaryotes - 241 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4156054..4158004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202945.2 → NP_001189874.1  ribonuclease PH45A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189874.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LGD7, Q9LDM2
    UniProtKB/TrEMBL
    A0A5S9XCZ7, A0A654F7N7, A0A7G2ENK4
    Conserved Domains (1) summary
    cd11368
    Location:11 → 272
    RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome

  2. NM_001338017.1 → NP_001319535.1  ribonuclease PH45A [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H1ZEI6
    Conserved Domains (1) summary
    cd11368
    Location:11 → 214
    RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome

  3. NM_001338018.1 → NP_001327698.1  ribonuclease PH45A [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VEU1, A0A1I9LT43, A0A384LNX5, A0A7G2ENK4

  4. NM_112136.5 → NP_566441.1  ribonuclease PH45A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566441.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LGD7, Q9LDM2
    UniProtKB/TrEMBL
    A0A5S9XCZ7, A0A654F7N7, A0A7G2ENK4
    Conserved Domains (1) summary
    cd11368
    Location:11 → 272
    RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LDM2.1

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