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Aha1 domain-containing protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820379, updated on 18-Sep-2024

Summary

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Official Full Name
Aha1 domain-containing protein
Primary source
TAIR:AT3G12050
Locus tag
AT3G12050
See related
Araport:AT3G12050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MEC18.18
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (3839101..3841606)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene transmembrane/coiled-coil protein (Protein of unknown function DUF106, transmembrane) Neighboring gene DNA-3-methyladenine glycosylase (MAG) Neighboring gene trichome birefringence-like protein (DUF828) Neighboring gene RAB geranylgeranyl transferase beta subunit 2 Neighboring gene GTP-binding family protein Neighboring gene tetraspanin6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_112039.3
NM_180235.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Aha1 domain-containing protein
NP_566410.1
  • Aha1 domain-containing protein; FUNCTIONS IN: ATPase activator activity, chaperone binding; INVOLVED IN: response to stress; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Activator of Hsp90 ATPase, N-terminal (InterPro:IPR015310), Activator of Hsp90 ATPase homologue 1-like (InterPro:IPR013538); Has 600 Blast hits to 579 proteins in 214 species: Archae - 0; Bacteria - 24; Metazoa - 217; Fungi - 180; Plants - 73; Viruses - 0; Other Eukaryotes - 106 (source: NCBI BLink).
NP_850566.1
  • Aha1 domain-containing protein; FUNCTIONS IN: ATPase activator activity, chaperone binding; INVOLVED IN: response to stress; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Activator of Hsp90 ATPase, N-terminal (InterPro:IPR015310), Activator of Hsp90 ATPase homologue 1-like (InterPro:IPR013538); Has 501 Blast hits to 499 proteins in 203 species: Archae - 0; Bacteria - 24; Metazoa - 214; Fungi - 142; Plants - 65; Viruses - 0; Other Eukaryotes - 56 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3839101..3841606
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112039.3 → NP_566410.1  Aha1 domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566410.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V504, A0A384LMS3, Q8L863, Q9LHL7
    Conserved Domains (2) summary
    cd08892
    Location:225 → 358
    SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins
    pfam09229
    Location:29 → 163
    Aha1_N; Activator of Hsp90 ATPase, N-terminal

  2. NM_180235.1 → NP_850566.1  Aha1 domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850566.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4J8L7, Q8L863
    Conserved Domains (3) summary
    cd08892
    Location:186 → 319
    SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins
    COG5580
    Location:20 → 320
    COG5580; Activator of HSP90 ATPase [Posttranslational modification, protein turnover, chaperones]
    pfam09229
    Location:31 → 125
    Aha1_N; Activator of Hsp90 ATPase, N-terminal
Nucleotide Protein
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