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ATE2 arginine-tRNA protein transferase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820295, updated on 18-Sep-2024

Summary

Official Symbol
ATE2
Official Full Name
arginine-tRNA protein transferase 2
Primary source
TAIR:AT3G11240
Locus tag
AT3G11240
See related
Araport:AT3G11240
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
arginine-tRNA protein transferase 2; ATATE2
Summary
Encodes an arginyl-tRNA:protein arginyltransferase (ATE2), a component of the N-end rule pathway that targets protein degradation through the identity of the amino-terminal residue of specific protein substrates. Arabidopsis contains two ATE genes: At5g05700/ATE1, At3g11240/ATE2. Another component of the N-end rule pathway is At5g02310/PROTEOLYSIS6 (PRT6). PRT6 and ATE were shown to regulate seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination.
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Genomic context

See ATE2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (3518472..3521188, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene alfin-like 2 Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene Paxneb protein-like protein Neighboring gene Yippee family putative zinc-binding protein Neighboring gene Ribosomal protein L10 family protein Neighboring gene WUSCHEL related homeobox 5

General gene information

NM_001337920.1
NM_001337921.1
NM_001337922.1
NM_111959.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables arginyl-tRNA--protein transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 
located_in nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
arginine-tRNA protein transferase 2
NP_187733.1
  • arginine-tRNA protein transferase 2 (ATE2); FUNCTIONS IN: arginyltransferase activity; INVOLVED IN: regulation of seed germination, regulation of lipid catabolic process, protein arginylation, response to abscisic acid stimulus; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Arginine-tRNA-protein transferase, N-terminal (InterPro:IPR007471), Arginine-tRNA-protein transferase 1, eukaryotic (InterPro:IPR017137), Arginine-tRNA-protein transferase, C-terminal (InterPro:IPR007472); BEST Arabidopsis thaliana protein match is: arginine-tRNA protein transferase 1 (TAIR:AT5G05700.1); Has 2270 Blast hits to 2031 proteins in 783 species: Archae - 0; Bacteria - 1438; Metazoa - 213; Fungi - 241; Plants - 48; Viruses - 0; Other Eukaryotes - 330 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3518472..3521188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001337919.1NP_001326206.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNK5
  2. NM_111959.3NP_187733.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187733.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9C776
    UniProtKB/TrEMBL
    A0A5S9XCE8
    Conserved Domains (3) summary
    smart01016
    Location:161273
    Arg_tRNA_synt_N; Arginyl tRNA synthetase N terminal dom
    pfam04376
    Location:32105
    ATE_N; Arginine-tRNA-protein transferase, N terminus
    pfam04377
    Location:322468
    ATE_C; Arginine-tRNA-protein transferase, C terminus
  3. NM_001337921.1NP_001326208.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNK5
  4. NM_001337920.1NP_001326207.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNK3, A0A5S9XCE8
  5. NM_001337922.1NP_001326209.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LNK5