U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EMB2804 tubulin folding cofactor B [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820184, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
EMB2804
Official Full Name
tubulin folding cofactor B
Primary source
TAIR:AT3G10220
Locus tag
AT3G10220
See related
Araport:AT3G10220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMBRYO DEFECTIVE 2804
Summary
Encodes a tubulin-binding cofactor. Homozygous mutant plants are embryo lethal. Heterozygous mutant plants showed increased ploidy and higher numbers of spindles and phragmoplasts, suggesting a role in cell division.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See EMB2804 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (3161706..3164231)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Putative membrane lipoprotein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein Neighboring gene ncRNA Neighboring gene lycopene cyclase Neighboring gene ncRNA Neighboring gene F-box and associated interaction domains-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. AtTFC B is involved in control of cell division. Du Y, et al. Front Biosci (Elite Ed), 2010 Jan 1. PMID 20036919
  2. Arabidopsis tubulin folding cofactor B interacts with alpha-tubulin in vivo. Dhonukshe P, et al. Plant Cell Physiol, 2006 Oct. PMID 16928693
  3. Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins. Van Damme D, et al. Plant J, 2004 Nov. PMID 15469496
  4. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AtTFC B plays an important role in plant cell division.
    Title: AtTFC B is involved in control of cell division.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NM_111857.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alpha-tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in post-chaperonin tubulin folding pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in tubulin complex assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in phragmoplast HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tubulin folding cofactor B
NP_187633.2
  • tubulin folding cofactor B; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: tubulin complex assembly, embryo development, cell division; LOCATED IN: nucleus, cytoplasm, phragmoplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytoskeleton-associated protein, CAP-Gly (InterPro:IPR000938); Has 1750 Blast hits to 1417 proteins in 212 species: Archae - 0; Bacteria - 0; Metazoa - 1247; Fungi - 285; Plants - 70; Viruses - 0; Other Eukaryotes - 148 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3161706..3164231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111857.5 → NP_187633.2  tubulin folding cofactor B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187633.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q67XW4, Q67Z52, Q8L5R5, Q9SS34
    UniProtKB/TrEMBL
    A0A178VKX4, A0A5S9XB09, A0A654F5P2
    Conserved Domains (2) summary
    smart01052
    Location:161 → 228
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    pfam14560
    Location:14 → 96
    Ubiquitin_2; Ubiquitin-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q67Z52.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools