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DFC DHFS-FPGS homolog C [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820179, updated on 18-Sep-2024

Summary

Official Symbol
DFC
Official Full Name
DHFS-FPGS homolog C
Primary source
TAIR:AT3G10160
Locus tag
AT3G10160
See related
Araport:AT3G10160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
A. THALIANA DHFS-FPGS HOMOLOG C; ATDFC; DHFS-FPGS homolog C; folylpolyglutamate synthetase 2; FPGS2
Summary
Encodes a protein with tetrahydrofolylpolyglutamate synthase activity that is located in the mitochondrial matrix. One of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
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Genomic context

See DFC in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Sequence:
Chromosome: 3; NC_003074.8 (3139383..3144615, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RECA homolog 3 Neighboring gene ncRNA Neighboring gene purple acid phosphatase 16 Neighboring gene ncRNA Neighboring gene Gibberellin-regulated family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Calcium-binding EF-hand family protein

General protein information

Preferred Names
DHFS-FPGS homolog C
NP_187627.3
  • DHFS-FPGS homolog C (DFC); CONTAINS InterPro DOMAIN/s: Mur ligase, central (InterPro:IPR013221), Folylpolyglutamate synthetase, conserved site (InterPro:IPR018109), Mur ligase, C-terminal (InterPro:IPR004101), Folylpolyglutamate synthetase (InterPro:IPR001645); BEST Arabidopsis thaliana protein match is: DHFS-FPGS homolog B (TAIR:AT5G05980.2); Has 7721 Blast hits to 7719 proteins in 2542 species: Archae - 43; Bacteria - 4847; Metazoa - 165; Fungi - 368; Plants - 133; Viruses - 0; Other Eukaryotes - 2165 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3139383..3144615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111851.6NP_187627.3  DHFS-FPGS homolog C [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187627.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2RVP0, F4J2K2, Q8W038, Q9SR80
    UniProtKB/TrEMBL
    A0A5S9XBW1
    Conserved Domains (1) summary
    PLN02881
    Location:68625
    PLN02881; tetrahydrofolylpolyglutamate synthase