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OMR1 L-O-methylthreonine resistant 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820166, updated on 18-Sep-2024

Summary

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Official Symbol
OMR1
Official Full Name
L-O-methylthreonine resistant 1
Primary source
TAIR:AT3G10050
Locus tag
AT3G10050
See related
Araport:AT3G10050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
L-O-methylthreonine resistant 1; THREONINE DEHYDRATASE/DEAMINASE
Summary
first enzyme in the biosynthetic pathway of isoleucine
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Genomic context

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See OMR1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (3098725..3102048, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene sequence-specific DNA binding transcription factor Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene TBP-associated factor 12 Neighboring gene RmlC-like cupins superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. L-O-Methylthreonine-Resistant Mutant of Arabidopsis Defective in Isoleucine Feedback Regulation. Mourad G, et al. Plant Physiol, 1995 Jan. PMID 12228340, Free PMC Article
  2. Arabidopsis methionine gamma-lyase is regulated according to isoleucine biosynthesis needs but plays a subordinate role to threonine deaminase. Joshi V, et al. Plant Physiol, 2009 Sep. PMID 19571310, Free PMC Article
  3. Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids. Niehaus TD, et al. Plant Cell, 2014 Jul. PMID 25070638, Free PMC Article
  4. A Regulatory Hierarchy of the Arabidopsis Branched-Chain Amino Acid Metabolic Network. Xing A, et al. Plant Cell, 2017 Jun. PMID 28522547, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_111840.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables threonine deaminase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables threonine deaminase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in isoleucine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within isoleucine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within isoleucine biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
L-O-methylthreonine resistant 1
NP_187616.1
  • L-O-methylthreonine resistant 1 (OMR1); FUNCTIONS IN: L-threonine ammonia-lyase activity; INVOLVED IN: isoleucine biosynthetic process, threonine metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Threonine dehydratase I (InterPro:IPR005787), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Threonine dehydratase, C-terminal (InterPro:IPR001721), Serine/threonine dehydratase, pyridoxal-phosphate-binding site (InterPro:IPR000634); BEST Arabidopsis thaliana protein match is: serine racemase (TAIR:AT4G11640.1); Has 26917 Blast hits to 26860 proteins in 2759 species: Archae - 692; Bacteria - 18712; Metazoa - 552; Fungi - 889; Plants - 577; Viruses - 2; Other Eukaryotes - 5493 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    3098725..3102048 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111840.3 → NP_187616.1  L-O-methylthreonine resistant 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187616.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SPF1, Q9ZSS6
    UniProtKB/TrEMBL
    A0A178VHF4, A0A5S9XAY2, Q8GUG5
    Conserved Domains (1) summary
    PLN02550
    Location:1 → 592
    PLN02550; threonine dehydratase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZSS6.1

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