ATB' BETA Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ATB' BETA
Official Full Name: Protein phosphatase 2A regulatory B subunit family protein
Primary source: TAIR:AT3G09880
Locus tag: AT3G09880
See related: Araport:AT3G09880
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Summary: Encodes B' regulatory subunit of PP2A (AtB'beta).
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Genomic context

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See ATB' BETA in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 2

Sequence:: Chromosome: 3; NC_003074.8 (3029471..3032399)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The combined absence of the regulatory subunits protein phosphatase 2A (PP2AB'alpha and PP2AB'beta) leads to the premature loss of chromosome cohesion in meiosis I.
Title: PROTEIN PHOSHATASE 2A B'α and β Maintain Centromeric Sister Chromatid Cohesion during Meiosis in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_111823.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within megasporogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within meiotic sister chromatid cohesion	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within microsporogenesis	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with condensed chromosome, centromeric region	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
part_of protein phosphatase type 2A complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Protein phosphatase 2A regulatory B subunit family protein

NP_187599.1

ATB' BETA; FUNCTIONS IN: protein phosphatase type 2A regulator activity; INVOLVED IN: signal transduction; LOCATED IN: protein phosphatase type 2A complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2A, regulatory B subunit, B56 (InterPro:IPR002554); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2A regulatory B subunit family protein (TAIR:AT5G03470.1); Has 1186 Blast hits to 1156 proteins in 194 species: Archae - 0; Bacteria - 0; Metazoa - 571; Fungi - 167; Plants - 302; Viruses - 0; Other Eukaryotes - 146 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

3029471..3032399

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_111823.3 → NP_187599.1 Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_187599.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O04376

UniProtKB/TrEMBL

A0A178VQB1, A0A5S9XAK1

Conserved Domains (2) summary

pfam01603
Location:79 → 483

B56; Protein phosphatase 2A regulatory B subunit (B56 family)

cl27532
Location:29 → 91

B56; Protein phosphatase 2A regulatory B subunit (B56 family)