MAPKKK6 mitogen-activated protein kinase kinase kinase 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: MAPKKK6
Official Full Name: mitogen-activated protein kinase kinase kinase 6
Primary source: TAIR:AT3G07980
Locus tag: AT3G07980
See related: Araport:AT3G07980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MAP3K EPSILON PROTEIN KINASE 2; MAP3KE2; mitogen-activated protein kinase kinase kinase 6
Summary: MAP3K epsilon protein kinase 2 is functionally redundant with MAP3Ke1. Required for pollen development but not essential.
NEW: Try the new Gene table
Try the new Transcript table

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

MAP3Kepsilon2 is required for pollen viability in Arabidopsis.
Title: The protein kinase genes MAP3K epsilon 1 and MAP3K epsilon 2 are required for pollen viability in Arabidopsis thaliana.

Submit: New GeneRIF Correction

NM_001337757.1

NM_111677.4

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within plasma membrane organization	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within pollen development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in protein autophosphorylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of cell division	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info
located_in vacuole	HDA more info	PubMed

NP_187455.1

mitogen-activated protein kinase kinase kinase 6 (MAPKKK6); FUNCTIONS IN: protein serine/threonine kinase activity, binding, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: plasma membrane organization, pollen development; LOCATED IN: vacuole; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 7 (TAIR:AT3G13530.1); Has 136121 Blast hits to 133731 proteins in 5126 species: Archae - 192; Bacteria - 15089; Metazoa - 51503; Fungi - 13384; Plants - 33405; Viruses - 666; Other Eukaryotes - 21882 (source: NCBI BLink).

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain