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GLR1.4 glutamate receptor 1.4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819940, updated on 18-Sep-2024

Summary

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Official Symbol
GLR1.4
Official Full Name
glutamate receptor 1.4
Primary source
TAIR:AT3G07520
Locus tag
AT3G07520
See related
Araport:AT3G07520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATGLR1.4; glutamate receptor 1.4
Summary
member of Putative ligand-gated ion channel subunit family. Contains a functional cation - permeable pore domain. Involved in cellular cation homeostasis.
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Genomic context

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See GLR1.4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (2394891..2398291, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Far-red impaired responsive (FAR1) family protein Neighboring gene maternal effect embryo arrest protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene autophagocytosis-associated family protein Neighboring gene integrator complex subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A plant homolog of animal glutamate receptors is an ion channel gated by multiple hydrophobic amino acids. Tapken D, et al. Sci Signal, 2013 Jun 11. PMID 23757024
  2. Arabidopsis thaliana glutamate receptor ion channel function demonstrated by ion pore transplantation. Tapken D, et al. J Mol Biol, 2008 Oct 31. PMID 18625242
  3. Inter-subunit interactions between glutamate-like receptors in Arabidopsis. Price MB, et al. Plant Signal Behav, 2013. PMID 24300102, Free PMC Article
  4. The identity of plant glutamate receptors. Lacombe B, et al. Science, 2001 May 25. PMID 11379626
  5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that AtGLR1.4 accounts for methionine-induced membrane depolarization in leaves.
    Title: A plant homolog of animal glutamate receptors is an ion channel gated by multiple hydrophobic amino acids.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_111630.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glutamate receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables intracellularly ligand-gated monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic cation channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium-mediated signaling ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cellular response to amino acid stimulus ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within intracellular calcium ion homeostasis NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within intracellular monoatomic cation homeostasis IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to light stimulus NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glutamate receptor 1.4
NP_187408.2
  • glutamate receptor 1.4 (GLR1.4); FUNCTIONS IN: intracellular ligand-gated ion channel activity, cation channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus, cellular cation homeostasis; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Extracellular ligand-binding receptor (InterPro:IPR001828), Glutamate receptor-related (InterPro:IPR015683), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: Glutamate receptor family protein (TAIR:AT5G48400.2); Has 3364 Blast hits to 3306 proteins in 339 species: Archae - 5; Bacteria - 450; Metazoa - 2203; Fungi - 0; Plants - 628; Viruses - 0; Other Eukaryotes - 78 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    2394891..2398291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111630.2 → NP_187408.2  glutamate receptor 1.4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187408.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LGN1, Q8LGN2, Q9SRR4
    UniProtKB/TrEMBL
    A0A654F508
    Conserved Domains (5) summary
    cd06366
    Location:47 → 410
    PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
    cd13686
    Location:448 → 778
    GluR_Plant; Plant glutamate receptor domain; the type 2 periplasmic binding protein fold
    pfam00060
    Location:570 → 810
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:64 → 390
    ANF_receptor; Receptor family ligand binding region
    cl21456
    Location:476 → 657
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LGN1.2

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