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NHX4 sodium hydrogen exchanger 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819811, updated on 18-Sep-2024

Summary

Official Symbol
NHX4
Official Full Name
sodium hydrogen exchanger 4
Primary source
TAIR:AT3G06370
Locus tag
AT3G06370
See related
Araport:AT3G06370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATNHX4; F24P17.16; F24P17_16; sodium hydrogen exchanger 4
Summary
member of Sodium proton exchanger family
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Genomic context

See NHX4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
14
Sequence:
Chromosome: 3; NC_003074.8 (1929946..1934073, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene dehydroquinate dehydratase, putative / shikimate dehydrogenase Neighboring gene arabinogalactan protein 27 Neighboring gene tubby-like protein 9 Neighboring gene Uncharacterized protein family (UPF0497)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001337652.1
NM_111512.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables sodium ion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables sodium:proton antiporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of pH IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to salt stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
 
located_in plant-type vacuole HDA PubMed 
located_in vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sodium hydrogen exchanger 4
NP_187288.2
  • sodium hydrogen exchanger 4 (NHX4); FUNCTIONS IN: sodium:hydrogen antiporter activity, sodium ion transmembrane transporter activity; INVOLVED IN: response to salt stress, sodium ion transport; LOCATED IN: vacuolar membrane, plasma membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Na+/H+ exchanger, subfamily (InterPro:IPR004709), Cation/H+ exchanger, conserved region (InterPro:IPR018422), Cation/H+ exchanger (InterPro:IPR006153), Na+/H+ exchanger, isoforms 1-4, conserved region (InterPro:IPR018407); BEST Arabidopsis thaliana protein match is: sodium hydrogen exchanger 2 (TAIR:AT3G05030.1); Has 5892 Blast hits to 5885 proteins in 1663 species: Archae - 61; Bacteria - 4002; Metazoa - 840; Fungi - 131; Plants - 419; Viruses - 0; Other Eukaryotes - 439 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1929946..1934073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001337651.1NP_001327379.1  sodium hydrogen exchanger 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VAM2, A0A1I9LS48, A0A384KPV5, A0A7G2EG13
    Conserved Domains (1) summary
    TIGR00840
    Location:46470
    b_cpa1; sodium/hydrogen exchanger 3
  2. NM_001337650.1NP_001327378.1  sodium hydrogen exchanger 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LS49
  3. NM_111512.3NP_187288.2  sodium hydrogen exchanger 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187288.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q84WG1, Q9SQU0
    UniProtKB/TrEMBL
    A0A7G2EG13
    Conserved Domains (1) summary
    COG0025
    Location:52462
    NhaP; NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism]
  4. NM_001337652.1NP_001327377.1  sodium hydrogen exchanger 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VAM2, A0A1I9LS48, A0A384KPV5, A0A7G2EG13
    Conserved Domains (1) summary
    TIGR00840
    Location:46470
    b_cpa1; sodium/hydrogen exchanger 3