RPL18 ribosomal protein L18 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: RPL18
Official Full Name: ribosomal protein L18
Primary source: TAIR:AT3G05590
Locus tag: AT3G05590
See related: Araport:AT3G05590
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: CYTOPLASMIC RIBOSOMAL PROTEIN L18; F18C1.14; F18C1_14; ribosomal protein L18
Summary: Encodes cytoplasmic ribosomal protein L18.
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Genomic context

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See RPL18 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 5

Sequence:: Chromosome: 3; NC_003074.8 (1621355..1623052)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Suspensor-specific expression of RPL18aB could rescue the cell proliferation defects in rpl18aB suspensors.
Title: RPL18aB helps maintain suspensor identity during early embryogenesis.
The cell type-specific complementation of RPL18aB in rpl18aB was not able to recover the phenotype, indicating that RPL18aB may play an essential role in early cell fate determination. This work unravels a novel role in embryo development for a ribosomal protein, and provides insight into regulatory mechanism of early embryogenesis.
Title: Ribosomal protein L18aB is required for both male gametophyte function and embryo development in Arabidopsis.
The hes mutant role of the mitochondrial ribosomal L18 protein produced uncellularized endosperm and embryos arrested at the late globular stage. The mutant embryos differentiated partially on rescue medium with some forming callus.
Title: Developmentally regulated HEART STOPPER, a mitochondrially targeted L18 ribosomal protein gene, is required for cell division, differentiation, and seed development in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001337591.1

Supported by ESTs:

NM_001337592.1

Supported by ESTs:

NM_111432.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	TAS Traceable Author Statement more info

Process	Evidence Code	Pubs
involved_in translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	TAS Traceable Author Statement more info

Component	Evidence Code	Pubs
NOT located_in Golgi apparatus	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed
part_of cytosolic large ribosomal subunit	HDA more info	PubMed
part_of large ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of large ribosomal subunit	TAS Traceable Author Statement more info
located_in plant-type vacuole	HDA more info	PubMed
located_in vacuole	HDA more info	PubMed

General protein information

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Preferred Names: ribosomal protein L18

NP_187210.1

ribosomal protein L18 (RPL18); FUNCTIONS IN: structural constituent of ribosome; INVOLVED IN: translation; LOCATED IN: cytosolic large ribosomal subunit, plasma membrane, chloroplast, vacuole, large ribosomal subunit; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal protein L18e/L15 (InterPro:IPR021131), Ribosomal protein L18e (InterPro:IPR000039); BEST Arabidopsis thaliana protein match is: Ribosomal protein L18e/L15 superfamily protein (TAIR:AT5G27850.1); Has 786 Blast hits to 785 proteins in 305 species: Archae - 30; Bacteria - 0; Metazoa - 334; Fungi - 154; Plants - 130; Viruses - 0; Other Eukaryotes - 138 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

1621355..1623052

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_111432.4 → NP_187210.1 ribosomal protein L18 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_187210.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P42791, Q9M9W4

UniProtKB/TrEMBL

A0A178V8M9, A0A5S9X9D7, A0A654G4P0

Conserved Domains (1) summary

pfam17135
Location:2 → 187

Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e
NM_001337591.1 → NP_001327673.1 ribosomal protein L18 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LT16
NM_001337592.1 → NP_001327672.1 ribosomal protein L18 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LT16