U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HST ARM repeat superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819666, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
HST
Official Full Name
ARM repeat superfamily protein
Primary source
TAIR:AT3G05040
Locus tag
AT3G05040
See related
Araport:AT3G05040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
HASTY; HASTY 1; HST1; T9J14.1; T9J14_1
Summary
Encodes member of importin/exportin family. Involved in timing of shoot maturation. Involved in miRNA transport. Mutants flower early and have small, curled leaves and reduced abundance of certain miRNA species.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HST in Genome Data Viewer
Location:
chromosome: 3
Exon count:
22
Sequence:
Chromosome: 3; NC_003074.8 (1401171..1408302, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene exportin-4 protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene NOP56-like pre RNA processing ribonucleoprotein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. HASTY-mediated miRNA dynamics modulate nitrogen starvation-induced leaf senescence in Arabidopsis. Sakuraba Y, et al. Nat Commun, 2024 Sep 10. PMID 39256370, Free PMC Article
  2. HASTY, the Arabidopsis EXPORTIN5 ortholog, regulates cell-to-cell and vascular microRNA movement. Brioudes F, et al. EMBO J, 2021 Aug 2. PMID 34152631, Free PMC Article
  3. HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing. Cambiagno DA, et al. Mol Plant, 2021 Mar 1. PMID 33385584
  4. Nuclear processing and export of microRNAs in Arabidopsis. Park MY, et al. Proc Natl Acad Sci U S A, 2005 Mar 8. PMID 15738428, Free PMC Article
  5. HASTY: a gene that regulates the timing of shoot maturation in Arabidopsis thaliana. Telfer A, et al. Development, 1998 May. PMID 9550721

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HASTY-mediated miRNA dynamics modulate nitrogen starvation-induced leaf senescence in Arabidopsis.
    Title: HASTY-mediated miRNA dynamics modulate nitrogen starvation-induced leaf senescence in Arabidopsis.
  2. HASTY, the Arabidopsis EXPORTIN5 ortholog, regulates cell-to-cell and vascular microRNA movement.
    Title: HASTY, the Arabidopsis EXPORTIN5 ortholog, regulates cell-to-cell and vascular microRNA movement.
  3. HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing.
    Title: HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing.
  4. analysis of catalytic reactions of the homogentisate prenyl transferase involved in plastoquinone-9 biosynthesis
    Title: Catalytic reactions of the homogentisate prenyl transferase involved in plastoquinone-9 biosynthesis.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_001337559.1
NM_111376.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables nuclear export signal receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables nuclear export signal receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within leaf morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within miRNA export from nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in miRNA export from nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of flower development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within polarity specification of adaxial/abaxial axis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein export from nucleus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within shoot system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope NAS
Non-traceable Author Statement
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ARM repeat superfamily protein
NP_187155.2
  • HASTY (HST); CONTAINS InterPro DOMAIN/s: Exportin-1/Importin-beta-like (InterPro:IPR013598), Armadillo-type fold (InterPro:IPR016024); Has 520 Blast hits to 417 proteins in 141 species: Archae - 0; Bacteria - 0; Metazoa - 205; Fungi - 183; Plants - 102; Viruses - 0; Other Eukaryotes - 30 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1401171..1408302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111376.4 → NP_187155.2  ARM repeat superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187155.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WP44, Q84UC4, Q9CAW7
    UniProtKB/TrEMBL
    A0A178VI74, A0A654F5L5
    Conserved Domains (1) summary
    pfam08389
    Location:106 → 266
    Xpo1; Exportin 1-like protein

  2. NM_001337559.1 → NP_001327303.1  ARM repeat superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VI74, A0A1I9LRW7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0WP44.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools