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LRB1 BTB/POZ/Kelch-associated protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819234, updated on 18-Sep-2024

Summary

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Official Symbol
LRB1
Official Full Name
BTB/POZ/Kelch-associated protein
Primary source
TAIR:AT2G46260
Locus tag
AT2G46260
See related
Araport:AT2G46260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
light-response BTB 1; T3F17.9
Summary
Involvement in protein ubiquitylation is predicted based on physical interaction with CULLIN 3 proteins.
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Genomic context

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See LRB1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (18995645..18998672)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene myosin heavy chain-like protein Neighboring gene ncRNA Neighboring gene G-box binding factor 3 Neighboring gene TGF-beta receptor interacting protein 1 Neighboring gene Transducin/WD40 repeat-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The light-response BTB1 and BTB2 proteins assemble nuclear ubiquitin ligases that modify phytochrome B and D signaling in Arabidopsis. Christians MJ, et al. Plant Physiol, 2012 Sep. PMID 22732244, Free PMC Article
  2. MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signaling. Lechner E, et al. Dev Cell, 2011 Dec 13. PMID 22172674
  3. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LRB1 (LIGHT-RESPONSE BTB1) and LRB2 (LIGHT-RESPONSE BTB2) are involved in many developmental processes mediated by phytochrome B and phytochrome D.
    Title: The light-response BTB1 and BTB2 proteins assemble nuclear ubiquitin ligases that modify phytochrome B and D signaling in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_130189.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to red light IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
BTB/POZ/Kelch-associated protein
NP_566069.1
  • BTB/POZ/Kelch-associated protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/Kelch-associated (InterPro:IPR011705), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: POZ/BTB containin G-protein 1 (TAIR:AT3G61600.1); Has 3374 Blast hits to 3358 proteins in 97 species: Archae - 0; Bacteria - 0; Metazoa - 3133; Fungi - 0; Plants - 140; Viruses - 10; Other Eukaryotes - 91 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18995645..18998672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130189.3 → NP_566069.1  BTB/POZ/Kelch-associated protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566069.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82343, Q56WV2, Q8LG00, Q94AI9
    UniProtKB/TrEMBL
    A0A178VTN1, A0A5S9X7G9
    Conserved Domains (2) summary
    smart00875
    Location:266 → 351
    BACK; BTB And C-terminal Kelch
    cd18186
    Location:144 → 226
    BTB_POZ_ZBTB_KLHL-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing (ZBTB) proteins, Kelch-like (KLHL) proteins, and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O82343.2

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