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SLD2 Fatty acid/sphingolipid desaturase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819228, updated on 18-Sep-2024

Summary

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Official Symbol
SLD2
Official Full Name
Fatty acid/sphingolipid desaturase
Primary source
TAIR:AT2G46210
Locus tag
AT2G46210
See related
Araport:AT2G46210
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtSLD2; sphingoid LCB desaturase 2; T3F17.14
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Genomic context

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See SLD2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (18977344..18979309)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U11/U12 small nuclear ribonucleoprotein Neighboring gene DUF2358 family protein (DUF2358) Neighboring gene ncRNA Neighboring gene ABI-1-like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sphingolipid Δ8 unsaturation is important for glucosylceramide biosynthesis and low-temperature performance in Arabidopsis. Chen M, et al. Plant J, 2012 Mar. PMID 22023480
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_130183.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables sphingolipid 8-(E/Z)-desaturase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to cold IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sphingolipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Fatty acid/sphingolipid desaturase
NP_182144.1
  • Fatty acid/sphingolipid desaturase; FUNCTIONS IN: oxidoreductase activity, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, iron ion binding, heme binding; INVOLVED IN: oxidation reduction, fatty acid biosynthetic process, lipid metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid desaturase, type 1 (InterPro:IPR005804), Fatty acid/sphingolipid desaturase (InterPro:IPR012171), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: Fatty acid/sphingolipid desaturase (TAIR:AT3G61580.1); Has 5941 Blast hits to 5850 proteins in 906 species: Archae - 2; Bacteria - 1188; Metazoa - 1112; Fungi - 1689; Plants - 939; Viruses - 2; Other Eukaryotes - 1009 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18977344..18979309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130183.4 → NP_182144.1  Fatty acid/sphingolipid desaturase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182144.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EBF7
    UniProtKB/TrEMBL
    A0A178VWW6, A0A5S9X7P2
    Conserved Domains (2) summary
    cd03506
    Location:142 → 404
    Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
    pfam00173
    Location:11 → 82
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3EBF7.1

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