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CYP86A8 cytochrome P450, family 86, subfamily A, polypeptide 8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819205, updated on 18-Sep-2024

Summary

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Official Symbol
CYP86A8
Official Full Name
cytochrome P450, family 86, subfamily A, polypeptide 8
Primary source
TAIR:AT2G45970
Locus tag
AT2G45970
See related
Araport:AT2G45970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
''cytochrome P450; cytochrome P450; F4I18.5; family 86; LACERATA; LCR; polypeptide 8; polypeptide 8''; subfamily A
Summary
Encodes a member of the CYP86A subfamily of cytochrome p450 genes. Expressed at moderate levels in flowers, leaves, roots and stems.
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Genomic context

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See CYP86A8 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (18912095..18914739, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF295) Neighboring gene SKP1-like 20 Neighboring gene plasma membrane intrinsic protein 1B Neighboring gene mesoderm induction early response protein Neighboring gene ribosomal RNA small subunit methyltransferase G Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analysis of the LACERATA gene of Arabidopsis provides evidence for different roles of fatty acid omega -hydroxylation in development. Wellesen K, et al. Proc Natl Acad Sci U S A, 2001 Aug 14. PMID 11493698, Free PMC Article
  2. Differential expression and evolution of the Arabidopsis CYP86A subfamily. Duan H, et al. Plant Physiol, 2005 Mar. PMID 15709153, Free PMC Article
  3. Identification of novel seed longevity genes related to oxidative stress and seed coat by genome-wide association studies and reverse genetics. Renard J, et al. Plant Cell Environ, 2020 Oct. PMID 32519347
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_130160.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alkane 1-monooxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables aromatase activity IEA
Inferred from Electronic Annotation
more info
  
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within lipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within seed coat development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cytochrome P450, family 86, subfamily A, polypeptide 8
NP_182121.1
  • ''cytochrome P450, family 86, subfamily A, polypeptide 8'' (CYP86A8); FUNCTIONS IN: alkane 1-monooxygenase activity, oxygen binding; INVOLVED IN: fatty acid metabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 86, subfamily A, polypeptide 4 (TAIR:AT1G01600.1); Has 27979 Blast hits to 27896 proteins in 1493 species: Archae - 44; Bacteria - 2538; Metazoa - 10315; Fungi - 6189; Plants - 7925; Viruses - 3; Other Eukaryotes - 965 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18912095..18914739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130160.3 → NP_182121.1  cytochrome P450, family 86, subfamily A, polypeptide 8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182121.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80823
    UniProtKB/TrEMBL
    A0A5S9X7C3, A0A7G2EHA1
    Conserved Domains (1) summary
    cd11064
    Location:67 → 503
    CYP86A; cytochrome P450 family 86, subfamily A
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O80823.1

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