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PMM phosphomannomutase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819187, updated on 18-Sep-2024

Summary

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Official Symbol
PMM
Official Full Name
phosphomannomutase
Primary source
TAIR:AT2G45790
Locus tag
AT2G45790
See related
Araport:AT2G45790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPMM; F4I18.23; phosphomannomutase; PHOSPHOMANNOMUTASE
Summary
encodes a phosphomannomutase, involved in ascorbate biosynthesis
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Genomic context

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See PMM in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (18855675..18858018)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene signal recognition particle receptor protein, chloroplast (FTSY) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GATA type zinc finger transcription factor family protein Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Remorin family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CML10, a variant of calmodulin, modulates ascorbic acid synthesis. Cho KM, et al. New Phytol, 2016 Jan. PMID 26315131
  2. Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana. Qian W, et al. Plant J, 2007 Feb. PMID 17217471
  3. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
  4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
  5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_130142.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables phosphomannomutase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphomannomutase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in GDP-mannose biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within L-ascorbic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 

General protein information

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Preferred Names
phosphomannomutase
NP_182103.1
  • phosphomannomutase (PMM); FUNCTIONS IN: protein binding, phosphomannomutase activity; INVOLVED IN: L-ascorbic acid biosynthetic process, response to salt stress, mannose biosynthetic process; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Eukaryotic phosphomannomutase (InterPro:IPR005002), HAD-superfamily hydrolase, subfamily IIB (InterPro:IPR006379); Has 1083 Blast hits to 1081 proteins in 282 species: Archae - 1; Bacteria - 92; Metazoa - 201; Fungi - 171; Plants - 223; Viruses - 0; Other Eukaryotes - 395 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18855675..18858018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130142.4 → NP_182103.1  phosphomannomutase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182103.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80840, Q1W379
    UniProtKB/TrEMBL
    A0A178W2D7, A0A5S9X7B1, A0A7G2EHQ0
    Conserved Domains (1) summary
    PLN02423
    Location:1 → 245
    PLN02423; phosphomannomutase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O80840.1

Gene LinkOut

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