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CYP76C4 cytochrome P450, family 76, subfamily C, polypeptide 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819163, updated on 18-Sep-2024

Summary

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Official Symbol
CYP76C4
Official Full Name
cytochrome P450, family 76, subfamily C, polypeptide 4
Primary source
TAIR:AT2G45550
Locus tag
AT2G45550
See related
Araport:AT2G45550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
''cytochrome P450; cytochrome P450; F17K2.8; family 76; polypeptide 4; polypeptide 4''; subfamily C
Summary
member of CYP76C
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Genomic context

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See CYP76C4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (18773517..18775797, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene WD-40 repeat family protein / beige-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytochrome P450, family 76, subfamily C, polypeptide 1 Neighboring gene cytochrome P450, family 76, subfamily C, polypeptide 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Geraniol hydroxylase and hydroxygeraniol oxidase activities of the CYP76 family of cytochrome P450 enzymes and potential for engineering the early steps of the (seco)iridoid pathway. Höfer R, et al. Metab Eng, 2013 Nov. PMID 23933465
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CYP76B6 emerged as a highly specialized multifunctional enzyme catalyzing two sequential oxidation steps leading to the formation of 8-oxogeraniol from geraniol
    Title: Geraniol hydroxylase and hydroxygeraniol oxidase activities of the CYP76 family of cytochrome P450 enzymes and potential for engineering the early steps of the (seco)iridoid pathway.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 8-hydroxygeraniol dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cytochrome P450, family 76, subfamily C, polypeptide 4
NP_182079.1
  • ''cytochrome P450, family 76, subfamily C, polypeptide 4'' (CYP76C4); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: oxidation reduction; EXPRESSED IN: stem, root, carpel; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 76, subfamily C, polypeptide 1 (TAIR:AT2G45560.1); Has 35109 Blast hits to 34843 proteins in 1784 species: Archae - 57; Bacteria - 4750; Metazoa - 11986; Fungi - 7467; Plants - 9491; Viruses - 6; Other Eukaryotes - 1352 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18773517..18775797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130117.2 → NP_182079.1  cytochrome P450, family 76, subfamily C, polypeptide 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182079.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64635
    UniProtKB/TrEMBL
    A0A178VUL7
    Conserved Domains (1) summary
    cd11073
    Location:66 → 504
    CYP76-like; cytochrome P450 family 76 and similar cytochrome P450s
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64635.1

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