U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RAB6A Ras-related small GTP-binding family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819069, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
RAB6A
Official Full Name
Ras-related small GTP-binding family protein
Primary source
TAIR:AT2G44610
Locus tag
AT2G44610
See related
Araport:AT2G44610
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATRAB6A; ATRABH1B; F16B22.10; RAB6
Summary
Encodes a GTP-binding protein with similarity to yeast YPT6 . RAB6 can complement the yeast YTP mutant.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RAB6A in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (18411424..18414153, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DYNAMIN-like 1D Neighboring gene uncharacterized protein Neighboring gene mitochondrial acyl carrier protein 1 Neighboring gene Galactose oxidase/kelch repeat superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Rab-H1b is essential for trafficking of cellulose synthase and for hypocotyl growth in Arabidopsis thaliana. He M, et al. J Integr Plant Biol, 2018 Nov. PMID 29975455
  2. A small GTP-binding protein from Arabidopsis thaliana functionally complements the yeast YPT6 null mutant. Bednarek SY, et al. Plant Physiol, 1994 Feb. PMID 8159788, Free PMC Article
  3. AtRAB-H1b and AtRAB-H1c GTPases, homologues of the yeast Ypt6, target reporter proteins to the Golgi when expressed in Nicotiana tabacum and Arabidopsis thaliana. Johansen JN, et al. J Exp Bot, 2009. PMID 19454595
  4. Fluorescence lifetime imaging of interactions between Golgi tethering factors and small GTPases in plants. Osterrieder A, et al. Traffic, 2009 Aug. PMID 19490533
  5. Localization and domain characterization of Arabidopsis golgin candidates. Latijnhouwers M, et al. J Exp Bot, 2007. PMID 18182439

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Differential subcelluar locations and stability of AtRAB-H1b and AtRAB-H1c altered in their GTP and membrane binding capacity.
    Title: AtRAB-H1b and AtRAB-H1c GTPases, homologues of the yeast Ypt6, target reporter proteins to the Golgi when expressed in Nicotiana tabacum and Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_130025.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within plant-type cell wall cellulose biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within secretion by cell IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
colocalizes_with Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endosome HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 
located_in trans-Golgi network HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Ras-related small GTP-binding family protein
NP_181989.1
  • RAB6A; FUNCTIONS IN: protein binding, GTP binding; INVOLVED IN: secretion by cell; LOCATED IN: plasma membrane, membrane fraction; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab6-related (InterPro:IPR015600); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog H1E (TAIR:AT5G10260.1); Has 26612 Blast hits to 26583 proteins in 727 species: Archae - 21; Bacteria - 159; Metazoa - 14143; Fungi - 3598; Plants - 2938; Viruses - 20; Other Eukaryotes - 5733 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18411424..18414153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130025.5 → NP_181989.1  Ras-related small GTP-binding family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181989.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80501
    UniProtKB/TrEMBL
    A0A178W0B3, A0A5S9X7A8
    Conserved Domains (1) summary
    cd01861
    Location:10 → 170
    Rab6; Rab GTPase family 6 (Rab6)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O80501.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.