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ROL5 repressor of lrx1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819035, updated on 18-Sep-2024

Summary

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Official Symbol
ROL5
Official Full Name
repressor of lrx1
Primary source
TAIR:AT2G44270
Locus tag
AT2G44270
See related
Araport:AT2G44270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F4I1.8; repressor of lrx1
Summary
Encodes ROL5, a repressor of lrx1 mutants that develop aberrant root hairs. ROL5 is a homolog of yeast Ncs6p that affects TOR signaling. The target of rapamycin (TOR) pathway is a major regulator of cell growth in eukaryotes, and inhibition of this pathway by rapamycin reduces cell growth. ROL5 might function as a mitochondrial component of the TOR pathway that influences the plant's response to ROS (reactive oxygen species).
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Genomic context

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See ROL5 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (18297878..18300304, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene tRNA-splicing ligase, putative (DUF239) Neighboring gene ncRNA Neighboring gene DUF946 family protein (DUF946) Neighboring gene ncRNA Neighboring gene Major facilitator superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The cytosolic thiouridylase CTU2 of Arabidopsis thaliana is essential for posttranscriptional thiolation of tRNAs and influences root development. Philipp M, et al. BMC Plant Biol, 2014 Apr 28. PMID 24774365, Free PMC Article
  2. The TOR pathway modulates the structure of cell walls in Arabidopsis. Leiber RM, et al. Plant Cell, 2010 Jun. PMID 20530756, Free PMC Article
  3. Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway. Iñigo S, et al. Plant Physiol, 2016 Oct. PMID 27503603, Free PMC Article
  4. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of plant-type cell wall organization or biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to reactive oxygen species IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
repressor of lrx1
NP_181956.2
  • repressor of lrx1 (ROL5); FUNCTIONS IN: ATP binding; INVOLVED IN: response to reactive oxygen species, regulation of plant-type cell wall organization or biogenesis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Uncharacterised protein family UPF0021, C-terminal (InterPro:IPR000541), PP-loop (InterPro:IPR011063), 2-thiocytidine tRNA biosynthesis protein, TtcA (InterPro:IPR012089); BEST Arabidopsis thaliana protein match is: 2-thiocytidine tRNA biosynthesis protein, TtcA (TAIR:AT1G76170.1); Has 5057 Blast hits to 4981 proteins in 1812 species: Archae - 336; Bacteria - 3752; Metazoa - 169; Fungi - 215; Plants - 64; Viruses - 0; Other Eukaryotes - 521 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18297878..18300304 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129991.3 → NP_181956.2  repressor of lrx1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181956.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64862, Q8GZ19
    UniProtKB/TrEMBL
    A0A178VUZ0, A0A5S9X772, A0A654FCD4
    Conserved Domains (2) summary
    cd01993
    Location:61 → 247
    Alpha_ANH_like_II; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
    cl25646
    Location:211 → 312
    zn-ribbon_14; Zinc-ribbon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64862.2

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