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ABCB6 P-glycoprotein 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818533, updated on 18-Sep-2024

Summary

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Official Symbol
ABCB6
Official Full Name
P-glycoprotein 6
Primary source
TAIR:AT2G39480
Locus tag
AT2G39480
See related
Araport:AT2G39480
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette B6; F12L6.14; F12L6_14; P-glycoprotein 6; PGP6
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Genomic context

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See ABCB6 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Sequence:
Chromosome: 2; NC_003071.7 (16477792..16485039, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cation efflux family protein Neighboring gene ribosomal protein L23AA Neighboring gene PsbP-like protein 2 Neighboring gene ncRNA Neighboring gene F-box family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport. Zhang Y, et al. Nat Commun, 2018 Oct 11. PMID 30310073, Free PMC Article
  2. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
  3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
  4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
  5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. a strong redundant role for the unstudied ABCB6 and ABCB20 genes in auxin transport and response, is reported.
    Title: A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001336781.1
NM_129506.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
P-glycoprotein 6
NP_181480.1
  • P-glycoprotein 6 (PGP6); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140); BEST Arabidopsis thaliana protein match is: P-glycoprotein 20 (TAIR:AT3G55320.1); Has 727628 Blast hits to 364161 proteins in 4096 species: Archae - 12661; Bacteria - 576901; Metazoa - 18207; Fungi - 12101; Plants - 9039; Viruses - 13; Other Eukaryotes - 98706 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    16477792..16485039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129506.2 → NP_181480.1  P-glycoprotein 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181480.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80635, Q8LPT1
    UniProtKB/TrEMBL
    A0A654F1L5
    Conserved Domains (3) summary
    PTZ00265
    Location:69 → 1389
    PTZ00265; multidrug resistance protein (mdr1); Provisional
    pfam00664
    Location:91 → 364
    ABC_membrane; ABC transporter transmembrane region
    cl21455
    Location:412 → 646
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. NM_001336781.1 → NP_001324134.1  P-glycoprotein 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VUH1, A0A1P8AZ84
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LPT1.2

Gene LinkOut

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