TFIIS transcript elongation factor IIS [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: TFIIS
Official Full Name: transcript elongation factor IIS
Primary source: TAIR:AT2G38560
Locus tag: AT2G38560
See related: Araport:AT2G38560
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: RDO2; REDUCED DORMANCY 2; T6A23.24; T6A23_24; transcript elongation factor IIS
Summary: Encodes RNA polymerase II transcript elongation factor TFIIS. Complements yeast TFIIS mutation. Mutant plants display essentially normal development, but they flower slightly earlier than the wild type and show clearly reduced seed dormancy.
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Genomic context

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See TFIIS in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 2

Sequence:: Chromosome: 2; NC_003071.7 (16134543..16136695)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Elongation factor TFIIS is essential for heat stress adaptation in plants.
Title: Elongation factor TFIIS is essential for heat stress adaptation in plants.
HUB1, RDO2 and VIP5 are involved in the regulation of both flowering time and seed dormancy. [RDO2]
Title: Identification of the Arabidopsis REDUCED DORMANCY 2 gene uncovers a role for the polymerase associated factor 1 complex in seed dormancy.
Data show that the down-regulation of DOG1 expression causes the seed dormancy phenotype of tfIIs mutants.
Title: The seed dormancy defect of Arabidopsis mutants lacking the transcript elongation factor TFIIS is caused by reduced expression of the DOG1 gene.
suggesting that down-regulation of DOG1 expression is involved in the seed dormancy phenotype of tfIIs mutants
Title: Reduced expression of the DOG1 gene in Arabidopsis mutant seeds lacking the transcript elongation factor TFIIS.
TFIIS(-/-) plants display essentially normal development, but they flower slightly earlier than control plants and show clearly reduced seed dormancy.
Title: Transcript elongation factor TFIIS is involved in arabidopsis seed dormancy.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_129413.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of flower development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of transcription elongation by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to gibberellin	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to heat	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within seed dormancy process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within seed germination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: transcript elongation factor IIS

NP_181390.1

transcript elongation factor IIS (TFIIS); CONTAINS InterPro DOMAIN/s: Zinc finger, TFIIS-type (InterPro:IPR001222), Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type (InterPro:IPR003617), Transcription elongation factor S-II, central domain (InterPro:IPR003618), Transcription factor IIS, N-terminal (InterPro:IPR017923), Transcription elongation factor S-IIM (InterPro:IPR017890), Transcription elongation factor, IIS (InterPro:IPR016492), Transcription elongation factor, TFIIS (InterPro:IPR006289), Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal (InterPro:IPR010990); BEST Arabidopsis thaliana protein match is: F-box family protein (TAIR:AT2G42730.1); Has 1858 Blast hits to 1830 proteins in 294 species: Archae - 58; Bacteria - 2; Metazoa - 702; Fungi - 370; Plants - 279; Viruses - 52; Other Eukaryotes - 395 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

16134543..16136695

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129413.4 → NP_181390.1 transcript elongation factor IIS [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181390.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8VXZ6, Q9ZVH8

UniProtKB/TrEMBL

A0A178VY86, A0A5S9X576

Conserved Domains (1) summary

TIGR01385
Location:21 → 378

TFSII; transcription elongation factor S-II