Ssr3 signal sequence receptor subunit 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ssr3provided by RGD
Official Full Name: signal sequence receptor subunit 3provided by RGD
Primary source: RGD:621630
See related: EnsemblRapid:ENSRNOG00000011148 AllianceGenome:RGD:621630
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SSR3 (signal sequence receptor subunit 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Liver (RPKM 944.9), Muscle (RPKM 708.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q31

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (151915101..151935162, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (149605005..149625069, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (156010997..156023853, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH139217 (e-PCR)
- UniSTS:221303

RH140109 (e-PCR)
- UniSTS:222189

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Sec61 translocon complex	NAS Non-traceable Author Statement more info	PubMed
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: translocon-associated protein subunit gamma

Names: SSR-gamma; TRAP-complex gamma subunit; TRAP-gamma; signal sequence receptor subunit gamma; signal sequence receptor, gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.