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SCY2 SecY protein transport family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817711, updated on 18-Sep-2024

Summary

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Official Symbol
SCY2
Official Full Name
SecY protein transport family protein
Primary source
TAIR:AT2G31530
Locus tag
AT2G31530
See related
Araport:AT2G31530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMB2289; EMBRYO DEFECTIVE 2289; SECY HOMOLOG 2; T9H9.5; T9H9_5
Summary
Encodes a component of the thylakoid-localized Sec system involved in the translocation of cytoplasmic proteins into plastid. Loss-of-function mutations result in arrest at the globular stage and embryo lethality.
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Genomic context

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See SCY2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Sequence:
Chromosome: 2; NC_003071.7 (13427011..13430632)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene neuronal acetylcholine receptor subunit alpha-5 Neighboring gene calcium-dependent protein kinase 24 Neighboring gene IBR domain-containing protein Neighboring gene pseudo Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene signal transducer/transcription protein, putative (DUF1685) Neighboring gene glutathione peroxidase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sorting of SEC translocase SCY components to different membranes in chloroplasts. Singhal R, et al. J Exp Bot, 2017 Nov 2. PMID 28992187, Free PMC Article
  2. The Sec2 translocase of the chloroplast inner envelope contains a unique and dedicated SECE2 component. Li Y, et al. Plant J, 2015 Nov. PMID 26406904
  3. Identification of Putative Substrates of SEC2, a Chloroplast Inner Envelope Translocase. Li Y, et al. Plant Physiol, 2017 Apr. PMID 28213560, Free PMC Article
  4. Plastids contain a second sec translocase system with essential functions. Skalitzky CA, et al. Plant Physiol, 2011 Jan. PMID 21051552, Free PMC Article
  5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The region of SCY2 that contains transmembrane domains 3 and 4 is necessary for localization to the inner envelope and may serve as a membrane anchor, enhancing the integration of other transmembrane domains via either stop-transfer or post-import mechanisms.
    Title: Sorting of SEC translocase SCY components to different membranes in chloroplasts.
  2. Data show that the SEC2 translocase consisting of SCY2, SECE2, and SECA2 likely integrates a subset of inner envelope membrane proteins.
    Title: Identification of Putative Substrates of SEC2, a Chloroplast Inner Envelope Translocase.
  3. Data indicate that SECE2 plays an essential role in plant growth and development, and specifically interacts with the SCY2 component in vivo.
    Title: The Sec2 translocase of the chloroplast inner envelope contains a unique and dedicated SECE2 component.
  4. SCY2 and SECA2 function in Sec-mediated integration and translocation processes at the inner envelope membrane.
    Title: Plastids contain a second sec translocase system with essential functions.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_128710.7

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
acts_upstream_of_or_within chloroplast organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within protein localization to chloroplast IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within thylakoid membrane organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plastid envelope IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SecY protein transport family protein
NP_180711.4
  • EMBRYO DEFECTIVE 2289 (EMB2289); FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein secretion, embryo development ending in seed dormancy; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SecY protein (InterPro:IPR002208); BEST Arabidopsis thaliana protein match is: SECY homolog 1 (TAIR:AT2G18710.1); Has 8827 Blast hits to 8825 proteins in 2687 species: Archae - 73; Bacteria - 5355; Metazoa - 4; Fungi - 0; Plants - 96; Viruses - 0; Other Eukaryotes - 3299 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13427011..13430632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128710.7 → NP_180711.4  SecY protein transport family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180711.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4IQV7, Q8W4F6, Q9SIQ4
    UniProtKB/TrEMBL
    A0A178VNV5, A0A5S9X3H1
    Conserved Domains (2) summary
    PRK09204
    Location:140 → 552
    secY; preprotein translocase subunit SecY; Reviewed
    pfam00344
    Location:207 → 553
    SecY; SecY translocase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4IQV7.1

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