U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GLX2-5 glyoxalase 2-5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817693, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
GLX2-5
Official Full Name
glyoxalase 2-5
Primary source
TAIR:AT2G31350
Locus tag
AT2G31350
See related
Araport:AT2G31350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
glyoxalase 2-5; T28P16.16; T28P16_16
Summary
Encodes a mitochondrial glyoxalase 2 that can accommodate a number of different metal centers and with the predominant metal center being Fe(III)Zn(II).
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See GLX2-5 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Sequence:
Chromosome: 2; NC_003071.7 (13368070..13371097)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene embryo defective 1381 Neighboring gene uncharacterized protein Neighboring gene 16:0delta9 desaturase 2 Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structural studies on a mitochondrial glyoxalase II. Marasinghe GP, et al. J Biol Chem, 2005 Dec 9. PMID 16227621, Free PMC Article
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

NM_128692.5
NM_179835.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
glyoxalase 2-5
NP_180693.1
  • glyoxalase 2-5 (GLX2-5); CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-4 (TAIR:AT1G06130.1); Has 16142 Blast hits to 16141 proteins in 2537 species: Archae - 414; Bacteria - 10534; Metazoa - 488; Fungi - 336; Plants - 226; Viruses - 0; Other Eukaryotes - 4144 (source: NCBI BLink).
NP_850166.1
  • glyoxalase 2-5 (GLX2-5); CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-4 (TAIR:AT1G06130.2); Has 16139 Blast hits to 16138 proteins in 2537 species: Archae - 414; Bacteria - 10534; Metazoa - 489; Fungi - 336; Plants - 226; Viruses - 0; Other Eukaryotes - 4140 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13368070..13371097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001336327.1 → NP_001324089.1  glyoxalase 2-5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AZ54

  2. NM_128692.5 → NP_180693.1  glyoxalase 2-5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180693.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EBQ9, Q9SID3
    UniProtKB/TrEMBL
    A0A5S9X317, A0A654EYY2, A0A7G2EFI8
    Conserved Domains (1) summary
    PLN02398
    Location:1 → 324
    PLN02398; hydroxyacylglutathione hydrolase

  3. NM_179835.1 → NP_850166.1  glyoxalase 2-5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850166.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EFI8
    Conserved Domains (3) summary
    PLN02398
    Location:1 → 323
    PLN02398; hydroxyacylglutathione hydrolase
    pfam16123
    Location:239 → 321
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:75 → 238
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SID3.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.