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ASP1 aspartate aminotransferase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817648, updated on 18-Sep-2024

Summary

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Official Symbol
ASP1
Official Full Name
aspartate aminotransferase 1
Primary source
TAIR:AT2G30970
Locus tag
AT2G30970
See related
Araport:AT2G30970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
aspartate aminotransferase 1; ASPARTATE AMINOTRANSFERASE 1; F7F1.18; F7F1_18
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Genomic context

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See ASP1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (13178829..13182050)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene FtsH extracellular protease family Neighboring gene ncRNA Neighboring gene myosin-M heavy chain-like protein Neighboring gene ncRNA Neighboring gene SHAGGY-related protein kinase dZeta Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene arginine N-methyltransferase, putative (DUF688)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recombinant expression, purification, and characterization of three isoenzymes of aspartate aminotransferase from Arabidopsis thaliana. Wilkie SE, et al. Protein Expr Purif, 1998 Apr. PMID 9535706
  2. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
  3. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article
  4. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
  5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001124949.1
NM_128651.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables L-aspartate:2-oxoglutarate aminotransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-aspartate:2-oxoglutarate aminotransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables copper ion binding HDA PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 2-oxoglutarate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in aspartate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glutamate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in peroxisome HDA PubMed 

General protein information

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Preferred Names
aspartate aminotransferase 1
NP_001118421.1
  • aspartate aminotransferase 1 (ASP1); FUNCTIONS IN: L-aspartate:2-oxoglutarate aminotransferase activity, copper ion binding; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 2 (TAIR:AT5G19550.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_180654.1
  • aspartate aminotransferase 1 (ASP1); FUNCTIONS IN: L-aspartate:2-oxoglutarate aminotransferase activity, copper ion binding; INVOLVED IN: response to cadmium ion; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 2 (TAIR:AT5G19550.1); Has 5625 Blast hits to 5619 proteins in 1351 species: Archae - 10; Bacteria - 3742; Metazoa - 486; Fungi - 406; Plants - 379; Viruses - 0; Other Eukaryotes - 602 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13178829..13182050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128651.5 → NP_180654.1  aspartate aminotransferase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180654.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P46643
    UniProtKB/TrEMBL
    A0A178VP87, A0A5S9X2R5
    Conserved Domains (2) summary
    PLN02397
    Location:10 → 429
    PLN02397; aspartate transaminase
    pfam00155
    Location:57 → 423
    Aminotran_1_2; Aminotransferase class I and II

  2. NM_001124949.1 → NP_001118421.1  aspartate aminotransferase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001118421.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P46643
    UniProtKB/TrEMBL
    A0A178VP87, A0A5S9X2R5
    Conserved Domains (2) summary
    PLN02397
    Location:10 → 429
    PLN02397; aspartate transaminase
    pfam00155
    Location:57 → 423
    Aminotran_1_2; Aminotransferase class I and II
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46643.1

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