CYP71A12 cytochrome P450 family 71 polypeptide [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CYP71A12
Official Full Name: cytochrome P450 family 71 polypeptide
Primary source: TAIR:AT2G30750
Locus tag: AT2G30750
See related: Araport:AT2G30750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: cytochrome P450; family 71; polypeptide 12; subfamily A; T11J7.14; T11J7_14
Summary: putative cytochrome P450
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Genomic context

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See CYP71A12 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 4

Sequence:: Chromosome: 2; NC_003071.7 (13099486..13101371, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.
Title: The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.
In contrast to cyp71a13 plants, in which camalexin accumulation is partially reduced, double mutants synthesized only traces of camalexin, demonstrating that CYP71A12 contributes to camalexin biosynthesis in leaf tissue.
Title: TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_128628.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within induced systemic resistance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to bacterium	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum lumen	IDA Inferred from Direct Assay more info

General protein information

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Preferred Names: cytochrome P450 family 71 polypeptide

NP_180633.3

cytochrome P450, family 71, subfamily A, polypeptide 12 (CYP71A12); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: response to bacterium; LOCATED IN: endomembrane system; EXPRESSED IN: stem, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 71, subfamily A, polypeptide 13 (TAIR:AT2G30770.1); Has 34196 Blast hits to 33993 proteins in 1718 species: Archae - 48; Bacteria - 4046; Metazoa - 11921; Fungi - 7292; Plants - 9674; Viruses - 3; Other Eukaryotes - 1212 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

13099486..13101371 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_128628.4 → NP_180633.3 cytochrome P450 family 71 polypeptide [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

F4INX7, O49340, Q8LPP9

UniProtKB/TrEMBL

A0A178VN27, A0A5S9X2U8, A0A654EXK9

Conserved Domains (1) summary

cd11072
Location:63 → 489

CYP71-like; cytochrome P450 family 71 and similar cytochrome P450s