U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FUC1 alpha-L-fucosidase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817355, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
FUC1
Official Full Name
alpha-L-fucosidase 1
Primary source
TAIR:AT2G28100
Locus tag
AT2G28100
See related
Araport:AT2G28100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alpha-L-fucosidase 1; ATFUC1; F24D13.11; F24D13_11
Summary
Encodes a protein with alpha-fucosidase activity. The activity was assessed on 2'-fucosyl-lactitol. AtFUC1 was not able to act on XXFG substrates, at least when heterologously expressed in <i>Pichia pastoris</i>. The enzyme has been postulated to act on fucosylated substrates other than xyloglucan oligosaccharides. was shown (<i>Pichia pastoris</i>) to hydrolyze fucose in 3- and 4-linkage, hence was characterized as alpha-L-3,4-fucosidase
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See FUC1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (11974663..11976600)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene ncRNA Neighboring gene replication factor-A carboxy-terminal domain protein Neighboring gene Exostosin family protein Neighboring gene Major facilitator superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Degradation pathway of plant complex-type N-glycans: identification and characterization of a key α1,3-fucosidase from glycoside hydrolase family 29. Kato S, et al. Biochem J, 2018 Jan 11. PMID 29212795
  2. Molecular cloning and characterization of a plant alpha1,3/4-fucosidase based on sequence tags from almond fucosidase I. Zeleny R, et al. Phytochemistry, 2006 Apr. PMID 16516937
  3. AtFXG1, an Arabidopsis gene encoding alpha-L-fucosidase active against fucosylated xyloglucan oligosaccharides. de La Torre F, et al. Plant Physiol, 2002 Jan. PMID 11788770, Free PMC Article
  4. VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Ceserani T, et al. Plant J, 2009 Mar. PMID 19000166, Free PMC Article
  5. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results showed that FUC1 is an alpha-1,3-fucosidase acting on plant complex-type N-glycans and elucidated the degradation pathway of plant complex-type N-glycans.
    Title: Degradation pathway of plant complex-type N-glycans: identification and characterization of a key α1,3-fucosidase from glycoside hydrolase family 29.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_128370.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alpha-L-fucosidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycoprotein catabolic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in plant-type vacuole HDA PubMed 
located_in secretory vesicle HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
alpha-L-fucosidase 1
NP_180377.2
  • alpha-L-fucosidase 1 (FUC1); FUNCTIONS IN: alpha-L-fucosidase activity; INVOLVED IN: glycoprotein catabolic process; LOCATED IN: vacuole; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 29 (InterPro:IPR000933), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); Has 2006 Blast hits to 1993 proteins in 389 species: Archae - 18; Bacteria - 1470; Metazoa - 203; Fungi - 6; Plants - 70; Viruses - 0; Other Eukaryotes - 239 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11974663..11976600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128370.3 → NP_180377.2  alpha-L-fucosidase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180377.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GW72, Q9ZUV2
    UniProtKB/TrEMBL
    A0A178VQ23, A0A5S9X1Y4, A0A654EYB3
    Conserved Domains (1) summary
    COG3669
    Location:28 → 477
    AfuC; Alpha-L-fucosidase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GW72.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools